Indications And Dose
All forms of epilepsy except typical absence seizures ▶BY MOUTH ▶Child 1 month–1 year: Initially 125 mg daily, dose to be taken at bedtime, then increased in steps of 125 mg every 3 days, adjusted according to response; maintenance 125–250 mg twice daily ▶Child 2–4 years: Initially 125 mg once daily, dose to be taken at bedtime, then increased in steps of 125 mg every 3 days, adjusted according to response; maintenance 250–375 mg twice daily ▶Child 5–8 years: Initially 125 mg once daily, dose to be taken at bedtime, then increased in steps of 125 mg every 3 days, adjusted according to response; maintenance 375–500 mg twice daily ▶Child 9–17 years: Initially 125 mg once daily, dose to be taken at bedtime, then increased in steps of 125 mg every 3 days, increased to 250 mg twice daily, then increased in steps of 250 mg every 3 days (max. per dose 750 mg twice daily), adjusted according to response ▶Adult: Initially 125 mg once daily, dose to be taken at bedtime, then increased in steps of 125 mg every 3 days, increased to 500 mg daily in 2 divided doses, then increased in steps of 250 mg every 3 days, adjusted according to response; maintenance 0.75–1.5 g daily in 2 divided doses Essential tremor ▶BY MOUTH ▶Adult: Initially 50 mg daily, then adjusted according to response to up to 750 mg daily, dose to be increased over 2–3 weeks
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