Drug reference
Urinary frequency, urgency and incontinence associated with overactive bladder ▶BY MOUTH USING IMMEDIATE-RELEASE MEDICINES ▶Adult: 15 mg 1–2 times a day, increased if necessary up to 15 mg 3 times a day ▶BY MOUTH USING MODIFIED-RELEASE CAPSULES ▶Adult: 30 mg once daily Urinary frequency, urgency and incontinence associated with neurogenic bladder instability ▶BY MOUTH USING IMMEDIATE-RELEASE MEDICINES ▶Adult: 15 mg 3 times a day
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The need for continuing therapy for urinary incontinence should be reviewed every 4–6 weeks until symptoms stabilise, and then every 6–12 months.
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→Appendix 1: propiverine
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▶Common or very common Abdominal pain. fatigue ▶Uncommon Taste altered. tremor ▶Rare or very rare Restlessness ▶Frequency not known Hallucination
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Manufacturer advises avoid (restriction of skeletal development in animals).
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Manufacturer advises avoid—present in milk in animal studies.
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Manufacturer advises caution in mild impairment; avoid in moderate to severe impairment (no information available).
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Manufacturer advises caution in mild or moderate impairment. Dose adjustments Max. daily dose 30 mg if eGFR less than 30 mL/minute/1.73m2.
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There can be variation in the licensing of different medicines containing the same drug. Modified-release capsule CAUTIONARY AND ADVISORY LABELS 3, 25 ▶Detrunorm XL (Advanz Pharma) Propiverine hydrochloride 30 mg Detrunorm XL 30mg capsules | 28 capsule P £24.45 DT = £24.45 Propiverine hydrochloride 45 mg Detrunorm XL 45mg capsules | 28 capsule P £27.90 DT = £27.90 Tablet CAUTIONARY AND ADVISORY LABELS 3 ▶Propiverine hydrochloride (Non-proprietary) Propiverine hydrochloride 15 mg Propiverine 15mg tablets | 56 tablet P £25.42 DT = £22.78 ▶Detrunorm (Advanz Pharma) Propiverine hydrochloride 15 mg Detrunorm 15mg tablets | 56 tablet P £18.00 DT = £22.78 eiiii F 820
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15 mg 1–2 times a day, increased if necessary up
First-line fragment. Read the complete Indications and Dose section above.
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30 mg once daily
First-line fragment. Read the complete Indications and Dose section above.
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15 mg 3 times a day
First-line fragment. Read the complete Indications and Dose section above.
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