Indications And Dose
Overdosage with intravenous injection of unfractionated heparin ▶BY INTRAVENOUS INJECTION ▶Adult: Dose to be administered at a rate not exceeding 5 mg/minute, 1 mg neutralises 80–100 units heparin when given within 15 minutes; if longer than 15 minute since heparin, less protamine required (consult product literature for details) as heparin rapidly excreted; maximum 50 mg Overdosage with intravenous infusion of unfractionated heparin ▶BY INTRAVENOUS INJECTION ▶Adult: 25–50 mg, to be administered once heparin infusion stopped at a rate not exceeding 5 mg/minute Overdosage with subcutaneous injection of unfractionated heparin ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 25–50 mg, to be administered at a rate not exceeding 5 mg/minute, 1 mg neutralises 100 units heparin, then (by intravenous infusion), any remaining dose to be administered over 8–16 hours; maximum 50 mg per course Overdosage with subcutaneous injection of low molecular weight heparin ▶BY INTRAVENOUS INJECTION, OR BY CONTINUOUS INTRAVENOUS INFUSION ▶Adult: Dose to be administered by intermittent intravenous injection at a rate not exceeding 5 mg/minute, 1 mg neutralises approx. 100 units low molecular weight heparin (consult product literature of low molecular weight heparin for details); maximum 50 mg
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