Drug reference

Pyridoxine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1163

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Deficiency states ▶BY MOUTH ▶Adult: 20–50 mg 1–3 times a day Isoniazid-induced neuropathy (prophylaxis) ▶BY MOUTH ▶Adult: 10–20 mg daily Isoniazid-induced neuropathy (treatment) ▶BY MOUTH ▶Adult: 50 mg 3 times a day Idiopathic sideroblastic anaemia ▶BY MOUTH ▶Adult: 100–400 mg daily in divided doses Prevention of penicillamine-induced neuropathy in Wilson’s disease ▶BY MOUTH ▶Adult: 20 mg daily Premenstrual syndrome ▶BY MOUTH ▶Adult: 50–100 mg daily l UNLICENSED USE Not licensed for prophylaxis of penicillamine-induced neuropathy in Wilson’s disease. Not licensed for treatment of premenstrual syndrome. Blood and nutrition

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Safety

Important Safety Information

Prolonged use of pyridoxine in a dose of 10 mg daily is considered safe but the long-term use of pyridoxine in a dose of 200 mg or more daily has been associated with neuropathy. The safety of long-term pyridoxine supplementation with doses above 10 mg daily has not been established.

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Side Effects

Peripheral neuritis Overdose Overdosage induces toxic effects.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: capsule, oral suspension, oral solution, solution for injection Tablet ▶Pyridoxine hydrochloride (Non-proprietary) Pyridoxine hydrochloride 10 mg Pyridoxine 10mg tablets | 28 tablet P £16.95–£16.98 DT = £16.98 | 500 tablet £15.99 Pyridoxine hydrochloride 20 mg Pyridoxine 20mg tablets | 500 tablet G s Pyridoxine hydrochloride 50 mg Pyridoxine 50mg tablets | 28 tablet P £31.02 DT = £18.90 Oral solution ▶PyriDose (TriOn Pharma Ltd) Pyridoxine hydrochloride 20 mg per 1 ml PyriDose 100mg/5ml oral solution | 100 ml £29.86 DT = £25.19 Capsule ▶Pyridoxine hydrochloride (Non-proprietary) Pyridoxine hydrochloride 100 mg Vitamin B6 100mg capsules | 100 capsule s | 120 capsule £5.50

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Dose text by age group

Adult

20–50 mg 1–3 times a day

First-line fragment. Read the complete Indications and Dose section above.

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Adult

10–20 mg daily

First-line fragment. Read the complete Indications and Dose section above.

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Adult

50 mg 3 times a day

First-line fragment. Read the complete Indications and Dose section above.

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Adult

100–400 mg daily in divided doses

First-line fragment. Read the complete Indications and Dose section above.

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Adult

20 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

50–100 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Pyridoxine hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 1163

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

PDF page 1163

Safety

Important Safety Information

PDF page 1163

Side Effects

Peripheral neuritis Overdose Overdosage induces toxic effects.

PDF page 1163

Dose and formulations

Medicinal Forms

PDF page 1163

Dose text by age group

Adult

20–50 mg 1–3 times a day

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

10–20 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

50 mg 3 times a day

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

100–400 mg daily in divided doses

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

20 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Adult

50–100 mg daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 1163

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.