Drug Action
Rasagiline is a monoamine-oxidase B inhibitor.
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Drug reference
Rasagiline is a monoamine-oxidase B inhibitor.
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Parkinson’s disease, used alone or as adjunct to co- beneldopa or co-careldopa for ’end-of-dose’ fluctuations ▶BY MOUTH ▶Adult: 1 mg daily
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→Appendix 1: MAO-B inhibitors
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▶Common or very common Abdominal pain. angina pectoris . arthralgia. arthritis. conjunctivitis. depression. dermatitis. dry mouth. fall. fever. flatulence. hallucination. headache. increased risk of infection. leucopenia. malaise. nausea. neoplasms. pain. postural hypotension. sleep disorders. urinary urgency. vertigo. vomiting. weight decreased ▶Uncommon Appetite decreased. confusion ▶Frequency not known Dopamine dysregulation syndrome. drowsiness. eating disorders. pathological gambling. psychiatric disorders. sexual dysfunction
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Manufacturer advises avoid—no information available.
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Use with caution—may suppress lactation.
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Manufacturer advises caution in mild impairment; avoid in moderate to severe impairment (risk of increased exposure).
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension, oral solution Tablet ▶Rasagiline (Non-proprietary) Rasagiline 1 mg Rasagiline 1mg tablets | 28 tablet P £70.72 DT = £2.38 ▶Azilect (Teva UK Ltd) Rasagiline 1 mg Azilect 1mg tablets | 28 tablet P £70.72 DT = £2.38
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Avoid abrupt withdrawal.
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1 mg daily
First-line fragment. Read the complete Indications and Dose section above.
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