Drug reference
Treatment of postmenopausal osteoporosis to reduce risk of vertebral or hip fractures ▶BY MOUTH ▶Adult: 1 tablet once weekly on day 1 of the weekly cycle, followed by 1 sachet daily on days 2–6 of the weekly cycle
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Actonel Combi ® effervescent granules contain calcium carbonate 2.5 g (calcium 1 g or Ca2+ 25 mmol) and colecalciferol 22 micrograms (880 units)/sachet.
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→Appendix 1: bisphosphonates. calcium salts. vitamin D substances
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Tablets should be swallowed whole with plenty of water while sitting or standing; to be taken on an empty stomach at least 30 minutes before breakfast (or another oral medicine); patient should stand or sit upright for at least 30 minutes after taking tablet. Granules should be stirred into a glass of water and after dissolution complete taken immediately.
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There can be variation in the licensing of different medicines containing the same drug. Tablets/Granules ▶Actonel Combi (Theramex HQ UK Ltd) Actonel Combi 35mg tablets and 1000mg/880unit effervescent granules sachets | 4 week supply P £19.12 eiiii F 765
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Patients or carers should be given advice on how to administer risedronate with calcium carbonate and colecalciferol tablets and granules.
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1 tablet once weekly on day 1 of the weekly
First-line fragment. Read the complete Indications and Dose section above.
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