Indications And Dose
Neuromuscular blockade (intermediate duration) during surgery and intubation ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 600 micrograms/kg; (by intravenous injection) maintenance 150 micrograms/kg, alternatively (by intravenous infusion) maintenance 300–600 micrograms/kg/hour, adjusted according to response ▶Elderly: Initially 600 micrograms/kg; (by intravenous injection) maintenance 75–100 micrograms/kg, alternatively (by intravenous infusion) maintenance up to 400 micrograms/kg/hour, adjusted according to response Neuromuscular blockade (intermediate duration) during intensive care ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: Initially 600 micrograms/kg, initial dose is optional; (by intravenous infusion) maintenance 300–600 micrograms/kg/hour for first hour, then (by intravenous infusion), adjusted according to response DOSES AT EXTREMES OF BODY-WEIGHT ▶To avoid excessive dosage in obese patients, dose should be calculated on the basis of ideal body-weight.
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