Names and pronunciation
(roe-mi-ploe′stim) Nplate
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Drug reference
(roe-mi-ploe′stim) Nplate
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Func. class.: Hematopoietin
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Chem. class.: Thrombopoietin recep- tor agonist
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USES: Chronic idiopathic thrombocy- topenic purpura in patients who have had an insufficient response to corticoste- roids, immunoglobulins, or splenectomy; hematopoietic syndrome of acute radia- tion syndrome
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CONTRAINDICATIONS: Hyper- sensitivity to this product or mannitol
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DOSAGE AND ROUTES Thrombocytopenia in chronic idiopathic thrombocytopenic purpura (ITP) • Adult: SUBCUT 1 mcg/kg/wk (based on actual body weight); increase the weekly dosage by 1 mcg/kg until platelet count ≥50,000/mm3; 10 mcg/kg/wk max
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Available forms: Injection 125-, 250-, 500-mcg single-use vials
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• Adult: SUBCUT 1 mcg/kg/wk (based on actual body weight); increase the weekly dosage by 1 mcg/kg until platelet count ≥50,000/mm3; 10 mcg/kg/wk max
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