Names and pronunciation
(sil-tux′-i-mab) Sylvant
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Drug reference
(sil-tux′-i-mab) Sylvant
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Func. class.: Antineoplastic: immune response modifier Func. class.: Antiflatulent
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USES: Multicentric Castleman dis- ease (MCD) patients who are HIV-neg- ative and human herpesvirus-8 (HHV-8)–negative USES: Flatulence
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Unlabeled uses: Dyspepsia
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CONTRAINDICATIONS Hypersensitivity CONTRAINDICATIONS: Hyper- sensitivity, GI obstruction/perforation S
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DOSAGE AND ROUTES • Adult: IV 11 mg/kg over 1 hr q3wk until treatment failure DOSAGE AND ROUTES • Adult and child >12 yr: PO 40-125 mg after meals and at bedtime prn, max 500 mg/day, 750 mg/day chewable • Child 2-12 yr: PO 40-50 mg after meals and at bedtime prn, max 480 mg/day • Child <2 yr: PO 20 mg qid prn, max 480 mg/day
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Available forms: Lyophilized powder for IV use: 100, 400 mg in single-dose vial See Appendix B See Appendix B See Appendix B (si-meth′i-kone) Barriere , Gas Relief , Gas- Relief, Gas Relief Extra Strength, Gas Relief Infants, Gas Relief Ultra Strength, Gas Relief, Gas-X Childrens, Gas-X Extra Strength, Gas-X Infant Drops, Gas-X Ultra Strength, Infants Gas Relief, Mi- Acid Gas Relief, Ovol , Phazyme
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• Adult and child >12 yr: PO 40-125 mg after meals and at bedtime prn, max 500 mg/day, 750 mg/day chewable
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• Child 2-12 yr: PO 40-50 mg after meals and at bedtime prn, max 480 mg/day
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• Child <2 yr: PO 20 mg qid prn, max 480 mg/day
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