Indications And Dose
Primary hypercholesterolaemia, or combined (mixed) hyperlipidaemia in patients who have not responded adequately to diet and other appropriate measures ▶BY MOUTH ▶Adult: 10–20 mg once daily, then increased if necessary up to 80 mg once daily, adjusted at intervals of at least 4 weeks, dose to be taken at night; 80 mg dose only for those with severe hypercholesterolaemia and at high risk of cardiovascular complications Homozygous familial hypercholesterolaemia in patients who have not responded adequately to diet and other appropriate measures ▶BY MOUTH ▶Adult: Initially 40 mg once daily, then increased if necessary up to 80 mg once daily, adjusted at intervals of at least 4 weeks, dose to be taken at night; 80 mg dose only for those with severe hypercholesterolaemia and at high risk of cardiovascular complications continued → Prevention of cardiovascular events in patients with atherosclerotic cardiovascular disease or diabetes mellitus ▶BY MOUTH Cardiovascular system ▶Adult: Initially 20–40 mg once daily, increased if necessary up to 80 mg once daily, adjusted at intervals of at least 4 weeks, dose to be taken at night; 80 mg dose only for those with severe hypercholesterolaemia and at high risk of cardiovascular complications
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