Drug reference
Adjunct to diet and exercise in mixed dyslipidaemia, when LDL-cholesterol levels are adequately controlled with the corresponding dose of simvastatin monotherapy (in patients at high cardiovascular risk) ▶BY MOUTH ▶Adult: 20/145 mg once daily, alternatively 40/145 mg once daily, dose should be based on previous simvastatin monotherapy dose
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History of pulmonary embolism
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→Appendix 1: fibrates. statins
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Manufacturer advises avoid if eGFR less than 60 mL/minute/1.73 m2; use with caution if eGFR 60–89 mL/minute/1.73 m2.
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There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 25 EXCIPIENTS: May contain Butylated hydroxyanisole, lecithin ▶Cholib (Mylan) Simvastatin 20 mg, Fenofibrate 145 mg Cholib 145mg/20mg tablets | 30 tablet P £7.71 DT = £7.71 Simvastatin 40 mg, Fenofibrate 145 mg Cholib 145mg/40mg tablets | 30 tablet P £8.33 DT = £8.33 LIPID MODIFYING DRUGS › OTHER
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20/145 mg once daily, alternatively 40/145 mg
First-line fragment. Read the complete Indications and Dose section above.
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