Indications And Dose
Active progressive rheumatoid arthritis (administered on expert advice) ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult: Test dose 10 mg, followed by 50 mg once weekly until there is definite evidence of remission, then reduced to 50 mg every 4 weeks continued for up to 5 years after complete remission, dose to be reduced gradually. Benefit is not expected until 300–500 mg has been given; it should be discontinued if there is no remission after 1 g has been given Relapse in patients who have previously received sodium aurothiomalate therapy for active progressive rheumatoid arthritis (administered on expert advice) ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult: 50 mg once weekly until control has been obtained again, then reduced to 50 mg every 4 weeks continued for up to 5 years after complete remission, if no response is seen within 2 months, alternative treatment should be sought
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