Indications And Dose
Acute myocardial infarction ▶BY INTRAVENOUS INFUSION ▶Adult: 1 500 000 units, to be initiated within 12 hours of symptom onset, dose to be given over 60 minutes Deep-vein thrombosis | Central retinal venous or arterial thrombosis ▶BY INTRAVENOUS INFUSION ▶Adult: 250 000 units, dose to be given over 30 minutes, then 100 000 units every 1 hour for 12 hours for central retinal venous or arterial thrombosis, or for 72 hours for deep-vein thrombosis Pulmonary embolism ▶BY INTRAVENOUS INFUSION ▶Adult: 250 000 units, dose to be given over 30 minutes, then 100 000 units every 1 hour for 24 hours, alternatively 1 500 000 units, dose to be given over 1–2 hours Occlusive peripheral arterial disease ▶BY INTRAVENOUS INFUSION ▶Adult: 250 000 units, dose to be given over 30 minutes, then 100 000 units every 1 hour for up to 5 days ▶BY INTRA-ARTERIAL INFUSION ▶Adult: (consult product literature)
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