Drug reference

Tamsulosin hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 850, 851

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Benign prostatic hyperplasia ▶BY MOUTH USING MODIFIED-RELEASE MEDICINES ▶Adult: 400 micrograms once daily

PDF page 850

Contra Indications

History of micturition syncope. history of postural hypotension

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Cautions

Care with initial dose (postural hypotension). cataract surgery (risk of intra-operative ﬂoppy iris syndrome). concomitant antihypertensives (reduced dosage and specialist supervision may be required). elderly CAUTIONS, FURTHER INFORMATION ▶Elderly For alpha1-selective adrenoceptor blockers, prescription potentially inappropriate (STOPP criteria): . in those with symptomatic orthostatic hypotension or micturition syncope (risk of precipitating recurrent syncope) . in those with persistent postural hypotension i.e. recurrent drop in systolic blood pressure 20 mmHg (risk of syncope and falls). See also Prescribing in the elderly p. 33.

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Exceptions To Legal Category

Tamsulosin hydrochloride 400 microgram capsules can be sold to the public for the treatment of functional symptoms of benign prostatic hyperplasia in men aged 45–75 years to be taken for up to 6 weeks before clinical assessment by a doctor.

PDF page 850

Safety

Interactions

→Appendix 1: alpha blockers

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Side Effects

▶Common or very common Dizziness. sexual dysfunction ▶Uncommon Asthenia. constipation. diarrhoea. headache. nausea. palpitations. postural hypotension. rhinitis. skin reactions. vomiting ▶Rare or very rare Angioedema. Stevens-Johnson syndrome . syncope ▶Frequency not known Dry mouth. epistaxis. vision disorders

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Hepatic Impairment

Manufacturer advises avoid in severe impairment.

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Renal Impairment

Use with caution if eGFR less than 10 mL/minute/1.73 m2.

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Dose and formulations

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Modified-release tablet CAUTIONARY AND ADVISORY LABELS 25 ▶Cositam XL (Consilient Health Ltd) Tamsulosin hydrochloride 400 microgram Cositam XL 400microgram tablets | 30 tablet P £8.89 DT = £10.47 ▶Faramsil (Sandoz Ltd) Tamsulosin hydrochloride 400 microgram Faramsil 400microgram modified-release tablets | 30 tablet P £8.89 DT = £10.47 ▶Flectone XL (Teva UK Ltd) Tamsulosin hydrochloride 400 microgram Flectone XL 400microgram tablets | 30 tablet P £9.95 DT = £10.47 ▶Flomaxtra XL (Astellas Pharma Ltd) Tamsulosin hydrochloride 400 microgram Flomaxtra XL 400microgram tablets | 30 tablet P £10.47 DT = £10.47 Modified-release capsule CAUTIONARY AND ADVISORY LABELS 25 ▶Tamsulosin hydrochloride (Non-proprietary) Tamsulosin hydrochloride 400 microgram Tamsulosin 400microgram modified-release capsules | 30 capsule P £3.87– £5.07 DT = £3.87 ▶Contiflo XL (Ranbaxy (UK) Ltd) Tamsulosin hydrochloride 400 microgram Contiflo XL 400microgram capsules | 30 capsule P £7.44 DT = £3.87 ▶Flomax MR (Sanofi) Tamsulosin hydrochloride 400 microgram Flomax Relief MR 400microgram capsules | 14 capsule p £5.58 | 28 capsule p £10.55 ▶Losinate MR (Consilient Health Ltd) Tamsulosin hydrochloride 400 microgram Losinate MR 400microgram capsules | 30 capsule P £10.14 DT = £3.87 | 200 capsule P £67.60 ▶Pamsvax XL (Actavis UK Ltd, Almus Pharmaceuticals Ltd) Tamsulosin hydrochloride 400 microgram Pamsvax XL 400microgram capsules | 30 capsule P £1.28 DT = £3.87 ▶Petyme MR (Teva UK Ltd) Tamsulosin hydrochloride 400 microgram Petyme 400microgram MR capsules | 30 capsule P £4.06 DT = £3.87 ▶Tabphyn MR (Genus Pharmaceuticals Ltd) Tamsulosin hydrochloride 400 microgram Tabphyn MR 400microgram capsules | 30 capsule P £4.45 DT = £3.87 ▶Tamfrex XL (Milpharm Ltd) Tamsulosin hydrochloride 400 microgram Tamfrex XL 400microgram capsules | 30 capsule P £28.51 DT = £3.87 ▶Tamsumac (Macleods Pharma UK Ltd) Tamsulosin hydrochloride 400 microgram Tamsumac 0.4mg modified-release capsules | 30 capsule P £3.87 DT = £3.87 ▶Tamurex (Somex Pharma) Tamsulosin hydrochloride 400 microgram Tamurex 400microgram modified-release capsules | 30 capsule P £3.87 DT = £3.87

PDF pages 850, 851

Clinical care

Patient And Carer Advice

Driving and skilled tasks May affect performance of skilled tasks e.g. driving.

PDF page 850

Dose text by age group

Adult

400 micrograms once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 850

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.

Drug reference

Tamsulosin hydrochloride

BNF 80 (2020–2021)

Source: BNF 80 (2020–2021)
PDF pages: 850, 851

Review source pages for extracted sections and age labels. BNF dose snippets show only their first line.

Overview

Indications And Dose

Benign prostatic hyperplasia ▶BY MOUTH USING MODIFIED-RELEASE MEDICINES ▶Adult: 400 micrograms once daily

PDF page 850

Contra Indications

History of micturition syncope. history of postural hypotension

PDF page 850

Cautions

PDF page 850

Exceptions To Legal Category

PDF page 850

Safety

Interactions

→Appendix 1: alpha blockers

PDF page 850

Side Effects

PDF page 850

Hepatic Impairment

Manufacturer advises avoid in severe impairment.

PDF page 850

Renal Impairment

Use with caution if eGFR less than 10 mL/minute/1.73 m2.

PDF page 850

Dose and formulations

Medicinal Forms

PDF pages 850, 851

Clinical care

Patient And Carer Advice

Driving and skilled tasks May affect performance of skilled tasks e.g. driving.

PDF page 850

Dose text by age group

Adult

400 micrograms once daily

First-line fragment. Read the complete Indications and Dose section above.

PDF page 850

Age labels are extracted for navigation. Check the complete source section and current local guidance before clinical use.