Names and pronunciation
(tek′oh-vir′i-mat)
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Drug reference
(tek′oh-vir′i-mat)
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Func. class.: Antiviral
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USES: Treatment of human smallpox disease, variola virus
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Unlabeled uses: Monkeypox virus
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CONTRAINDICATIONS Hypersensitivity
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DOSAGE AND ROUTES Smallpox • Adult 40 to ≤120 kg: PO: 600 mg bid × 14 days; IV 200 mg q12hr × 14 days; >120 kg: PO 600 mg (3 capsules) tid with meals for 14 days: IV 300 mg q12hr × 14 days • Child/adolescent: PO 13 to <25 kg: 200 mg bid × 14 days; 25 to <40 kg: 400 mg bid × 14 days; ≥40 kg: 600 mg bid × 14 days
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Available forms: Capsules 200 mg; solution for injection 200 mg/20 mL
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• Adult 40 to ≤120 kg: PO: 600 mg bid × 14 days; IV 200 mg q12hr × 14 days; >120 kg: PO 600 mg (3 capsules) tid with meals for 14 days: IV 300 mg q12hr × 14 days
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• Child/adolescent: PO 13 to <25 kg: 200 mg bid × 14 days; 25 to <40 kg: 400 mg bid × 14 days; ≥40 kg: 600 mg bid × 14 days
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