Drug reference
Androgen deficiency ▶BY MOUTH ▶Adult: 120–160 mg daily for 2–3 weeks; maintenance 40–120 mg daily Hypogonadism ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult (male): 1 g every 10–14 weeks, to be given over 2 minutes, if necessary, second dose may be given after 6 weeks to achieve rapid steady state plasma testosterone levels and then every 10–14 weeks.
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GENERAL SIDE-EFFECTS ▶Uncommon Diarrhoea. mood altered SPECIFIC SIDE-EFFECTS ▶Uncommon ▶With intramuscular use Appetite increased. arthralgia. breast abnormalities. cardiovascular disorder. cough. dysphonia. hypercholesterolaemia. increased risk of infection. migraine. muscle complaints. musculoskeletal stiffness. night sweats. pain in extremity. snoring. testicular disorders. tremor. urinary disorders. urinary tract disorder ▶Frequency not known ▶With intramuscular use Hair growth increased. spermatogenesis reduced ▶With oral use Azoospermia. fluid imbalance. gastrointestinal discomfort. hepatic function abnormal. lipid metabolism change. myalgia
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶Nebido (Bayer Plc) Testosterone undecanoate 250 mg per 1 ml Nebido 1000mg/4ml solution for injection vials | 1 vial P £87.11 DT = £87.11 e Capsule CAUTIONARY AND ADVISORY LABELS 21, 25 ▶Restandol (Merck Sharp & Dohme Ltd) Testosterone undecanoate 40 mg Restandol 40mg Testocaps | 30 capsule P £8.55 e | 60 capsule P £17.10 DT = £17.10 e 8.2a Male sex hormone antagonism ANTI-ANDROGENS
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120–160 mg daily for 2–3 weeks; maintenance
First-line fragment. Read the complete Indications and Dose section above.
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1 g every 10–14 weeks, to be given over
First-line fragment. Read the complete Indications and Dose section above.
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