Indications And Dose
Status epilepticus (only if other measures fail) ▶BY SLOW INTRAVENOUS INJECTION ▶Adult: 75–125 mg for 1 dose, to be administered as a 2.5% (25 mg/mL) solution Induction of anaesthesia ▶BY SLOW INTRAVENOUS INJECTION ▶Adult: Initially 100–150 mg, to be administered over 10–15 seconds usually as a 2.5% (25 mg/mL) solution, followed by 100–150 mg after 0.5–1 minute if required, dose to be given in fit and premedicated adults; debilitated patients or adults over 65 years may require a lower dose or increased administration time, alternatively initially up to 4 mg/kg (max. per dose 500 mg) Anaesthesia of short duration ▶BY SLOW INTRAVENOUS INJECTION ▶Adult: Initially 100–150 mg, to be administered over 10–15 seconds usually as a 2.5% (25 mg/mL) solution, followed by 100–150 mg after 0.5–1 minute if required, dose to be given in fit and premedicated adults; debilitated patients or adults over 65 years may require a lower dose or increased administration time, alternatively initially up to 4 mg/kg (max. per dose 500 mg) Reduction of raised intracranial pressure if ventilation controlled ▶BY SLOW INTRAVENOUS INJECTION ▶Adult: 1.5–3 mg/kg, repeated if necessary
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