Names and pronunciation
(thye-or-rid′a-zeen)
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Drug reference
(thye-or-rid′a-zeen)
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Func. class.: Antipsychotic (typical)
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Chem. class.: Phenothiazine piperidine
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USES: Psychotic disorders, schizo- phrenia, behavioral problems in children, anxiety, major depressive disorders, organic brain syndrome
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CONTRAINDICATIONS: Children <2 yr, hypersensitivity, coma, CNS depression
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Black Box Warning: QT prolongation, cardiac dysrhythmias, dementia-related psychosis, torsade de pointes
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DOSAGE AND ROUTES Schizophrenia • Adult: PO 50-100 mg tid, max 800 mg/day; dose gradually increased to de- sired response, then reduced to mini- mum maintenance Depression/behavioral problems/ dementia • Geriatric: PO 10-25 mg daily-tid, in- crease 4-7 days by 10-25 mg to desired dose, max 800 mg/day for short period
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Available forms: Tablet 10, 25, 50, 100
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• Adult: PO 50-100 mg tid, max 800 mg/day; dose gradually increased to de- sired response, then reduced to mini- mum maintenance Depression/behavioral problems/ dementia
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• Geriatric: PO 10-25 mg daily-tid, in- crease 4-7 days by 10-25 mg to desired dose, max 800 mg/day for short period
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