Drug reference
Chronic open-angle glaucoma | Ocular hypertension ▶TO THE EYE ▶Adult: Apply twice daily TIMOPTOL-LA ® Reduction of intra-ocular pressure in primary open-angle glaucoma ▶TO THE EYE ▶Adult: Apply once daily TIOPEX ® Reduction of intra-ocular pressure in primary open-angle glaucoma ▶TO THE EYE ▶Adult: Apply once daily, to be applied in the morning
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Also consider contra-indications listed for systemically administered beta blockers. bradycardia. heart block
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Consider also cautions listed for systemically administered beta blockers. patients with corneal disease
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Although multi-dose timolol eye drops commonly contain preservatives, preservative-free unit dose vials may be available.
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TIOPEX ® Scottish Medicines Consortium (SMC) decisions The Scottish Medicines Consortium has advised (February 2014) that timolol gel eye drops (Tiopex ®) are accepted for restricted use within NHS Scotland for the reduction of elevated intraocular pressure in patients with ocular hypertension or chronic open angle glaucoma who have proven sensitivity to preservatives.
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→Appendix 1: beta blockers, non-selective
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▶Common or very common Eye discomfort. eye disorders. eye inflammation. vision disorders SIDE-EFFECTS, FURTHER INFORMATION Systemic absorption can follow topical application to the eyes; consider side effects listed for systemically administered beta blockers.
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Manufacturer advises avoidance.
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There can be variation in the licensing of different medicines containing the same drug. Eye gel EXCIPIENTS: May contain Benzododecinium bromide ▶Timoptol-LA (Santen UK Ltd) Timolol (as Timolol maleate) 2.5 mg per 1 ml Timoptol-LA 0.25% ophthalmic gel-forming solution | 2.5 ml P £3.12 DT = £3.12 Timolol (as Timolol maleate) 5 mg per 1 ml Timoptol-LA 0.5% ophthalmic gel-forming solution | 2.5 ml P £3.12 DT = £3.12 Eye drops EXCIPIENTS: May contain Benzalkonium chloride ▶Timolol maleate (Non-proprietary) Timolol (as Timolol maleate) 2.5 mg per 1 ml Timolol 0.25% eye drops | 5 ml P £1.54 DT = £1.41 Timolol (as Timolol maleate) 5 mg per 1 ml Timolol 0.5% eye drops | 5 ml P £1.49 DT = £1.49 ▶Eysano (Aspire Pharma Ltd) Timolol (as Timolol maleate) 2.5 mg per 1 ml Eysano 2.5mg/ml eye drops | 5 ml P £8.45 DT = £8.45 Timolol (as Timolol maleate) 5 mg per 1 ml Eysano 5mg/ml eye drops | 5 ml P £9.65 DT = £9.65 ▶Timoptol (Santen UK Ltd) Timolol (as Timolol maleate) 2.5 mg per 1 ml Timoptol 0.25% eye drops | 5 ml P £3.12 DT = £1.41 Timolol (as Timolol maleate) 5 mg per 1 ml Timoptol 0.5% eye drops | 5 ml P £3.12 DT = £1.49 ▶Tiopex (Thea Pharmaceuticals Ltd) Timolol (as Timolol maleate) 1 mg per 1 gram Tiopex 1mg/g eye gel 0.4g unit dose | 30 unit dose P £7.49 DT = £7.49 Combinations available: Bimatoprost with timolol, p. 1250. Brimonidine with timolol, p. 1252. Brinzolamide with timolol, p. 1246. Dorzolamide with timolol, p. 1246. Latanoprost with timolol, p. 1248. Tafluprost with timolol, p. 1249. Travoprost with timolol, p. 1249 CARBONIC ANHYDRASE INHIBITORS
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Apply twice daily
First-line fragment. Read the complete Indications and Dose section above.
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Apply once daily
First-line fragment. Read the complete Indications and Dose section above.
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Apply once daily, to be applied in the morning
First-line fragment. Read the complete Indications and Dose section above.
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