Therapeutic Action
Antiprotozoal, antibacterial (group of nitroimidazoles)
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Drug reference
Antiprotozoal, antibacterial (group of nitroimidazoles)
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Amoebiasis, giardiasis, trichomoniasis Bacterial vaginitis, infections due to anaerobic bacteria (e.g. Clostridium sp, Bacteroides sp)
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Do not administer to patients with allergy to tinidazole or another nitroimidazole (metronidazole, secnidazole, etc.). May cause: gastrointestinal disturbances; rarely: allergic reactions, brownish urine, headache, dizziness. Risk of antabuse reaction when combined with alcohol. Administer with caution in patients taking oral anticoagulants (risk of haemorrhage), lithium, phenytoin (increased plasma concentrations of these drugs). Pregnancy: no contra-indication; divide into smaller doses, avoid prolonged use. Breast-feeding: significantly excreted in milk (risk of gastrointestinal disturbances in breastfed infants); divide into smaller doses, avoid prolonged use.
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500 mg tablet
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Amoebiasis Child: 50 mg/kg once daily (max. 2 g daily) Adult: 2 g once daily The treatment lasts 3 days in intestinal amoebiasis; 5 days in hepatic amoebiasis. Giardiasis, trichomoniasis and bacterial vaginitis Child: 50 mg/kg single dose (max. 2 g) Adult: 2 g single dose In the event of trichomoniasis, also treat sexual partner. Infections due to anaerobic bacteria Child over 12 years and adult: 2 g on D1 then 1 g once daily or 500 mg 2 times daily According to indication, tinidazole may be used in combination with other antibacterials; treatment duration depends on indication.
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– Below 25 °C
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2 g once daily
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2 g single dose
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2 g on D1 then 1 g once daily or 500 mg 2 times daily
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