Therapeutic Action
Opioid analgesic
PDF page 313
Loading InternPractice…
Drug reference
Opioid analgesic
PDF page 313
Moderate pain, alone or in combination with a non-opioid analgesic
PDF page 313
Do not administer in the event of severe respiratory depression and to patients that risk seizures (e.g. epilepsy, head injury, meningitis). May cause: dizziness, nausea, vomiting, drowsiness, dry mouth, sweating; rarely: allergic reactions, seizures, confusion; withdrawal symptoms; respiratory depression in the event of overdosage. Do not combine with opioid analgesics, including codeine. Avoid combination with carbamazepine, fluoxetine, chlorpromazine, promethazine, clomipramine, haloperidol, digoxin. Reduce doses by half and administer every 12 hours in elderly patients and in patients with severe renal or hepatic impairment (risk of accumulation). Pregnancy: no contra-indication. The neonate may develop withdrawal symptoms, respiratory depression and drowsiness in the event of prolonged administration of large doses at the end of rd the 3 trimester. In this event, closely monitor the neonate. Breast-feeding: use with caution, for a short period (2-3 days), at the lowest effective dose. Monitor the mother and the child: in the event of excessive drowsiness, stop treatment.
PDF pages 313, 314
50 mg capsule 100 mg/ml oral solution (1 drop = 2.5 mg)
PDF page 313
Child over 12 years and adult: 50 to 100 mg every 4 to 6 hours (max. 400 mg daily)
PDF page 313
According to clinical evolution; as short as possible. In the event of prolonged treatment, do not stop abruptly, reduce doses progressively.
PDF page 313
Tramadol is approximately 10 times less potent than morphine. In some countries, tramadol is on the list of narcotics: follow national regulations. Tramadol is not included in the WHO list of essential medicines.
PDF page 314
– – Below 25 °C
PDF page 314
50 to 100 mg every 4 to 6 hours (max. 400 mg daily)
PDF page 313