Indications And Dose
Facial acne ▶TO THE SKIN ▶Child 12–17 years: Apply daily, (to be applied thinly at bedtime) ▶Adult: Apply daily, (to be applied thinly at bedtime)
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Drug reference
Facial acne ▶TO THE SKIN ▶Child 12–17 years: Apply daily, (to be applied thinly at bedtime) ▶Adult: Apply daily, (to be applied thinly at bedtime)
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Perioral dermatitis. personal or familial history of skin cancer. rosacea
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Allow peeling (resulting from other irritant treatments) to subside before using a topical retinoid. avoid accumulation in angles of the nose. avoid contact with eyes, nostrils, mouth and mucous membranes, eczematous, broken or sunburned skin. avoid exposure to UV light (including sunlight, solariums). avoid use of topical retinoids with keratolytic agents, abrasive cleaners, comedogenic or astringent cosmetics. caution in sensitive areas such as the neck. severe acne
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→Appendix 1: clindamycin. retinoids
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Dry skin (discontinue if severe). eye irritation. oedema. photosensitivity reaction. skin pigmentation change (transient). skin reactions
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Females of child- bearing age must use effective contraception (oral progestogen-only contraceptives not considered effective).
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Contra-indicated in pregnancy.
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Amount of drug in milk after topical application probably too small to be harmful; ensure infant does not come in contact with treated areas.
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There can be variation in the licensing of different medicines containing the same drug. Gel CAUTIONARY AND ADVISORY LABELS 11 EXCIPIENTS: May contain Butylated hydroxytoluene, hydroxybenzoates (parabens), polysorbates ▶Treclin (Mylan) Tretinoin 250 microgram per 1 gram, Clindamycin (as Clindamycin phosphate) 10 mg per 1 gram Treclin 1%/0.025% gel | 30 gram P £11.94 DT = £11.94
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If sun exposure is unavoidable, an appropriate sunscreen or protective clothing should be used. Patients and carers should be warned that some redness and skin peeling can occur initially but settles with time. If undue irritation occurs, the frequency of application should be reduced or treatment suspended until the reaction subsides; if irritation persists, discontinue treatment. Several months of treatment may be needed to achieve an optimal response and the treatment should be continued until no new lesions develop.
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Apply daily, (to be applied thinly at
First-line fragment. Read the complete Indications and Dose section above.
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