Drug reference
Oedema | Potassium conservation with thiazide and loop diuretics ▶BY MOUTH ▶Adult: Initially 150–250 mg daily for 1 week, lower initial dose when given with other diuretics, then reduced to 150–250 mg daily on alternate days, to be taken in divided doses after breakfast and lunch
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Addison’s disease. anuria. hyperkalaemia
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Diabetes mellitus. elderly. gout. may cause blue fluorescence of urine
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→Appendix 1: potassium-sparing diuretics
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▶Common or very common Diarrhoea. hyperkalaemia. nausea. vomiting ▶Uncommon Dry mouth. headache. hyperuricaemia. renal failure (reversible on discontinuation). skin reactions ▶Rare or very rare Megaloblastic anaemia. nephritis tubulointerstitial. pancytopenia. photosensitivity reaction. serum sickness. urolithiasis ▶Frequency not known Asthenia. jaundice. metabolic acidosis
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Not used to treat gestational hypertension. Avoid unless essential.
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Present in milk—manufacturer advises avoid.
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Manufacturer advises caution; avoid in progressive impairment.
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Avoid in progressive impairment. Monitoring Monitor plasma-potassium concentration (high risk of hyperkalaemia in renal impairment).
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Monitor electrolytes.
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There can be variation in the licensing of different medicines containing the same drug. Capsule CAUTIONARY AND ADVISORY LABELS 14, 21 ▶Triamterene (Non-proprietary) Triamterene 50 mg Triamterene 50mg capsules | 30 capsule P £41.90 DT = £41.90 Combinations available: Co-triamterzide, p. 245. Furosemide with triamterene, p. 242
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Urine may look slightly blue in some lights.
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Initially 150–250 mg daily for 1 week, lower
First-line fragment. Read the complete Indications and Dose section above.
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