Drug reference
Urinary frequency | Urinary urgency | Urge incontinence ▶BY MOUTH USING IMMEDIATE-RELEASE MEDICINES ▶Adult: 20 mg twice daily, to be taken before food ▶BY MOUTH USING MODIFIED-RELEASE MEDICINES ▶Adult: 60 mg once daily
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The need for continuing therapy for urinary incontinence should be reviewed every 4–6 weeks until symptoms stabilise, and then every 6–12 months.
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→Appendix 1: trospium
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▶Common or very common Abdominal pain ▶Uncommon Chest pain. diarrhoea. flatulence ▶Rare or very rare Arthralgia. asthenia. dyspnoea. myalgia ▶Frequency not known Agitation. anaphylactic reaction. hallucination. severe cutaneous adverse reactions (SCARs)
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Manufacturer advises caution.
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Manufacturer advises caution.
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Manufacturer advises caution in mild to moderate impairment; avoid in severe impairment (no information available).
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Use with caution. Avoid Regurin ® XL. Dose adjustments Reduce dose to 20 mg once daily or 20 mg on alternate days if eGFR 10–30 mL/minute/1.73m2.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral solution Modified-release capsule CAUTIONARY AND ADVISORY LABELS 23, 25 ▶Regurin XL (Contura Ltd) Trospium chloride 60 mg Regurin XL 60mg capsules | 28 capsule P £23.05 DT = £23.05 Tablet CAUTIONARY AND ADVISORY LABELS 23 ▶Trospium chloride (Non-proprietary) Trospium chloride 20 mg Trospium chloride 20mg tablets | 60 tablet P £7.42 DT = £5.54 ▶Flotros (Galen Ltd) Trospium chloride 20 mg Flotros 20mg tablets | 60 tablet P £18.20 DT = £5.54 ▶Regurin (Mylan) Trospium chloride 20 mg Regurin 20mg tablets | 60 tablet P £26.00 DT = £5.54 ▶Uraplex (Contura Ltd) Trospium chloride 20 mg Uraplex 20mg tablets | 60 tablet P £26.00 DT = £5.54 BETA3-ADRENOCEPTOR AGONISTS
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20 mg twice daily, to be taken before food
First-line fragment. Read the complete Indications and Dose section above.
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60 mg once daily
First-line fragment. Read the complete Indications and Dose section above.
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