Drug reference
Prophylaxis against varicella infection ▶BY DEEP INTRAMUSCULAR INJECTION ▶Adult: 1 g, to be administered as soon as possible—not later than 10 days after exposure, second dose to be given if further exposure occurs more than 3 weeks after first dose, no evidence that effective in severe disease
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IgA deficiency. interference with live virus vaccines
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Available from selected Public Health England and NHS laboratories (also from BPL). l HANDLING AND STORAGE Care must be taken to store all immunological products under the conditions recommended in the product literature, otherwise the preparation may become ineffective. Refrigerated storage is usually necessary; many immunoglobulins need to be stored at 2–8°C and not allowed to freeze. Immunoglobulins should be protected from light. Opened multidose vials must be used within the period recommended in the product literature.
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→Appendix 1: immunoglobulins
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Arthralgia. chills. fever. headache. hypersensitivity. hypotension. malaise. nausea. skin reactions. tachycardia. vomiting
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Normal immunoglobulin for intravenous use may be used in those unable to receive intramuscular injections.
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There can be variation in the licensing of different medicines containing the same drug. Solution for injection ▶Varicella-Zoster (Bio Products Laboratory Ltd) Varicella-Zoster immunoglobulin human 250 mg Varicella-Zoster immunoglobulin human 250mg solution for injection vials | 1 vial P £600.00 DT = £600.00 Post-exposure prophylaxis IMMUNE SERA AND IMMUNOGLOBULINS › ANTITOXINS
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1 g, to be administered as soon as possible—not
First-line fragment. Read the complete Indications and Dose section above.
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