Drug reference
Pituitary diabetes insipidus ▶BY INTRAMUSCULAR INJECTION, OR BY SUBCUTANEOUS INJECTION ▶Adult: 5–20 units every 4 hours Initial control of oesophageal variceal bleeding ▶BY INTRAVENOUS INFUSION ▶Adult: 20 units, dose to be administered over 15 minutes
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Chronic nephritis (until reasonable blood nitrogen concentrations attained). vascular disease (especially disease of coronary arteries) unless extreme caution
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Asthma. avoid fluid overload. conditions which might be aggravated by water retention. epilepsy. heart failure. hypertension. migraine
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Abdominal pain. angina pectoris. bronchospasm. cardiac arrest. chest pain. diarrhoea. flatulence. fluid imbalance. gangrene. headache. hyperhidrosis. hypertension. musculoskeletal chest pain. nausea. pallor. peripheral ischaemia. tremor. urticaria. vertigo. vomiting
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Oxytocic effect in third trimester.
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Not known to be harmful.
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▶With intravenous use For intravenous infusion (argipressin), give intermittently in Glucose 5%; suggested concentration 20 units/100mL given over 15 minutes.
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There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: solution for injection Solution for injection ▶Vasopressin (Non-proprietary) Argipressin 20 unit per 1 ml Argipressin 20units/1ml solution for injection ampoules | 10 ampoule P £754.86–£950.00 (Hospital only) 1.2 Syndrome of inappropriate antidiuretic hormone secretion Other drugs used for Syndrome of inappropriate antidiuretic hormone secretion Demeclocycline hydrochloride, p. 597 DIURETICS › SELECTIVE VASOPRESSIN V2- RECEPTOR ANTAGONISTS
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5–20 units every 4 hours
First-line fragment. Read the complete Indications and Dose section above.
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20 units, dose to be administered over
First-line fragment. Read the complete Indications and Dose section above.
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