Names and pronunciation
(veh-neh′toh-klax) Venclexta
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Drug reference
(veh-neh′toh-klax) Venclexta
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Func. class.: Antineoplastic, signal transduction inhibitor
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USES: Treatment of CLL in patients with a 17p deletion who have received at least 1 prior therapy
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CONTRAINDICATIONS: Hypersensitivity, pregnancy
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DOSAGE AND ROUTES • Adult: PO 20 mg/day × 7 days, increase dose weekly × 5 wk: wk 2, 50 mg/day; wk 3, 100 mg/day; wk 4, 200 mg/day; wk 5 and beyond, 400 mg/day. Continue therapy until disease progression
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Available forms: Tablet 10, 50, 100 mg; starter pack
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• Adult: PO 20 mg/day × 7 days, increase dose weekly × 5 wk: wk 2, 50 mg/day; wk 3, 100 mg/day; wk 4, 200 mg/day; wk 5 and beyond, 400 mg/day. Continue therapy until disease progression
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