Indications And Dose
Hypersensitivity to wasp venom ▶BY SUBCUTANEOUS INJECTION Respiratory system ▶Adult: (consult product literature)
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Drug reference
Hypersensitivity to wasp venom ▶BY SUBCUTANEOUS INJECTION Respiratory system ▶Adult: (consult product literature)
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Consult product literature
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Consult product literature
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Each set of allergen extracts usually contains vials for the administration of graded amounts of allergen to patients undergoing hyposensitisation. Maintenance sets containing vials at the highest strength are also available. Product literature must be consulted for details of allergens, vial strengths, and administration.
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NICE decisions ▶Pharmalgen ® for bee and wasp venom allergy (February 2012) NICE TA246 Pharmalgen ® is an option for the treatment of IgE- mediated bee and wasp venom allergy in those who have had: . a severe systemic reaction to bee or wasp venom; . a moderate systemic reaction to bee or wasp venom and who have a raised baseline serum-tryptase concentration, a high risk of future stings, or anxiety about future stings. Treatment with Pharmalgen ® should be initiated and monitored in a specialist centre experienced in venom immunotherapy. www.nice.org.uk/guidance/ta246
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DESENSITISING VACCINES In view of concerns about the safety of desensitising vaccines, it is recommended that they are used by specialists and only for the following indications: . seasonal allergic hay fever (caused by pollen) that has not responded to anti-allergic drugs; . hypersensitivity to wasp and bee venoms. Manufacturer advises desensitising vaccines should generally be avoided or used with particular care in patients with asthma.
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→Appendix 1: wasp venom extract
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SIDE-EFFECTS, FURTHER INFORMATION Hypersensitivity reactions to wasp venom extracts can be life-threatening; cardiopulmonary resuscitation must be immediately available and patients need to be monitored for at least 1 hour after injection. If symptoms or signs of hypersensitivity develop (e.g. rash, urticaria, bronchospasm, faintness), even when mild, the patient should be observed until these have resolved completely.
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Avoid.
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There can be variation in the licensing of different medicines containing the same drug. Powder and solvent for solution for injection ▶Pharmalgen Wasp Venom (ALK-Abello Ltd) Wasp venom 120 nanogram Pharmalgen Wasp Venom 120nanogram powder and solvent for solution for injection vials | 1 vial P s Wasp venom 1.2 microgram Pharmalgen Wasp Venom 1.2microgram powder and solvent for solution for injection vials | 1 vial P s Wasp venom 12 microgram Pharmalgen Wasp Venom 12microgram powder and solvent for solution for injection vials | 1 vial P s Wasp venom 120 microgram Pharmalgen Wasp Venom maintenance set 120microgram vaccine powder and solvent for solution for injection vials | 4 vial P £150.00 2.1 Angioedema Other drugs used for Angioedema Adrenaline/epinephrine, p. 236 Respiratory system DRUGS USED IN HEREDITARY ANGIOEDEMA › COMPLEMENT REGULATORY PROTEINS
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(consult product literature)
First-line fragment. Read the complete Indications and Dose section above.
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