Drug reference
Schizophrenia and other psychoses ▶BY MOUTH ▶Adult: Initially 20–30 mg daily in divided doses, increased if necessary up to 150 mg daily; usual maintenance 20–50 mg daily (max. per dose 40 mg), for debilitated patients, use elderly dose ▶Elderly: Initially 5–15 mg daily in divided doses, increased if necessary up to 150 mg daily; usual maintenance 20–50 mg daily (max. per dose 40 mg)
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Apathetic states. CNS depression. comatose states. phaeochromocytoma. withdrawn states
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Hyperthyroidism. hypothyroidism
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→Appendix 1: zuclopenthixol
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Anxiety. appetite abnormal. asthenia. concentration impaired. confusion. depression. diarrhoea . dyspnoea. eye disorders. fever. flatulence. gait abnormal . gastrointestinal discomfort. glucose tolerance impaired. headaches. hepatic disorders. hot flush. hyperacusia. hyperglycaemia. hyperhidrosis. hyperlipidaemia. hypersalivation. hypothermia. malaise. memory loss. muscle complaints. nasal congestion. nausea. neuromuscular dysfunction. pain. palpitations. paraesthesia. photosensitivity reaction. reflexes increased . seborrhoea. sexual dysfunction. skin reactions. sleep disorders. speech disorder. syncope. thirst. thrombocytopenia. tinnitus. urinary disorders. vertigo. vision disorders. vulvovaginal dryness. weight decreased. withdrawal syndrome
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Manufacturer advises caution— monitor serum drug concentration. Dose adjustments Manufacturer advises dose reduction of half the recommended dose.
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Dose adjustments Halve dose in renal failure; smaller starting doses used in severe renal impairment because of increased cerebral sensitivity.
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There can be variation in the licensing of different medicines containing the same drug. Oral drops ▶Ciatyl-Z (Imported (Germany)) Zuclopenthixol (as Zuclopenthixol dihydrochloride) 20 mg per 1 ml Ciatyl-Z 20mg/ml oral drops | 30 ml P s Tablet CAUTIONARY AND ADVISORY LABELS 2 ▶Clopixol (Lundbeck Ltd) Zuclopenthixol (as Zuclopenthixol dihydrochloride) 2 mg Clopixol 2mg tablets | 100 tablet P £3.14 DT = £3.14 Zuclopenthixol (as Zuclopenthixol dihydrochloride) 10 mg Clopixol 10mg tablets | 100 tablet P £8.06 DT = £8.06 Zuclopenthixol (as Zuclopenthixol dihydrochloride) Nervous system 25 mg Clopixol 25mg tablets | 100 tablet P £16.13 DT = £16.13 eiiii F 401
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Initially 20–30 mg daily in divided doses,
First-line fragment. Read the complete Indications and Dose section above.
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