Therapeutic Action
Antiretroviral, HIV nucleoside reverse transcriptase inhibitor
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Individual generic drug information
Extracted information for ABACAVIR only.
Antiretroviral, HIV nucleoside reverse transcriptase inhibitor
Source page 19
HIV infection, in combination with other antiretrovirals
Source page 19
Extracted information for ABACAVIR only.
Do not administer to patients with severe hepatic impairment or history of hypersensitivity reaction to abacavir that led to discontinuation of treatment. Administer with caution to patients with hypertension, diabetes, hyperlipidaemia (might increase the risk of coronary disease). May cause: hypersensitivity reactions: fever, rash, gastrointestinal disturbances (nausea, vomiting, diarrhoea, abdominal pain), pharyngitis, cough, dyspnoea, malaise, headache, lethargy, myalgia, arthralgia; lactic acidosis, pancreatitis and hepatic disorders. In all these cases, stop taking abacavir immediately and permanently. Pregnancy: no contra-indication
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Extracted information for ABACAVIR only.
Fixed-dose combinations with lamivudine (3TC): 120 mg abacavir/60 mg lamivudine breakable and dispersible tablet 600 mg abacavir/300 mg lamivudine tablet
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The daily dose can be administered once daily or in 2 divided doses. Child 1 month and over and adult: Daily dose Weight 120/60 mg tablet 600/300 mg tablet ABC/3TC ½ tab x 2 3 to < 6 kg 120/60 mg – or 1 tab x 1 ½ tab morning and 1 tab evening 6 to < 10 kg 180/90 mg – or 1 ½ tab x 1 1 tab x 2 10 to < 14 kg 240/120 mg – or 2 tab x 1 1 tab morning and 1 ½ tab evening 14 to < 20 kg 300/150 mg – or 2 ½ tab x 1 1 ½ tab x 2 20 to < 25 kg 360/180 mg – or 3 tab x 1 ≥ 25 kg 600/300 mg – 1 tab x 1
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Depending on the efficacy and tolerance of abacavir.
Source page 20
Extracted information for ABACAVIR only.
Do not cut, crush or chew the 600/300 mg tablets. Also comes in fixed-dose combination 60 mg abacavir/30 mg lamivudine/5 mg dolutegravir dispersible tablet. Preferably use this formulation when available in children.
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– – Below 25 °C
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Filter the extracted dose blocks for this individual drug.