Individual generic drug information

amoxicillin

Reference monograph

Part of registered formulation

AMOXYCILLIN

Reference record: Amoxicillin
Source: BNF 80 (2020–2021)
Printed source pages: 601, 602, 603
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Amoxicillin only.

Indications And Dose

Susceptible infections (e.g. sinusitis, salmonellosis, oral infections) ▶BY MOUTH ▶Child 1–11 months: 125 mg 3 times a day; increased if necessary up to 30 mg/kg 3 times a day ▶Child 1–4 years: 250 mg 3 times a day; increased if necessary up to 30 mg/kg 3 times a day ▶Child 5–11 years: 500 mg 3 times a day; increased if necessary up to 30 mg/kg 3 times a day (max. per dose 1 g) ▶Child 12–17 years: 500 mg 3 times a day; increased if necessary up to 1 g 3 times a day, use increased dose in severe infections ▶Adult: 500 mg every 8 hours, increased if necessary to 1 g every 8 hours, increased dose used in severe infections ▶BY INTRAMUSCULAR INJECTION ▶Adult: 500 mg every 8 hours ▶BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION ▶Adult: 500 mg every 8 hours, increased to 1 g every 6 hours, use increased dose in severe infections Community-acquired pneumonia ▶BY MOUTH ▶Child 1–11 months: 125 mg 3 times a day for 5 days; increased if necessary up to 30 mg/kg continued → 3 times a day ▶Child 1–4 years: 250 mg 3 times a day for 5 days; increased if necessary up to 30 mg/kg 3 times a day ▶Child 5–11 years: 500 mg 3 times a day for 5 days; increased if necessary up to 30 mg/kg 3 times a day (max. per dose 1 g 3 times a day) ▶Child 12–17 years: 500 mg 3 times a day for 5 days; increased if necessary up to 1 g 3 times a day ▶Adult: 500 mg 3 times a day for 5 days; increased if necessary to 1 g 3 times a day Infection Acute exacerbation of bronchiectasis ▶BY MOUTH ▶Child 1–11 months: 125 mg 3 times a day for 7–14 days ▶Child 1–4 years: 250 mg 3 times a day for 7–14 days ▶Child 5–17 years: 500 mg 3 times a day for 7–14 days ▶Adult: 500 mg 3 times a day for 7–14 days Acute exacerbation of chronic obstructive pulmonary disease ▶BY MOUTH ▶Adult: 500 mg 3 times a day for 5 days, increased if necessary to 1 g 3 times a day, increased dose used in severe infections ▶BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION ▶Adult: 500 mg every 8 hours, increased to 1 g every 6 hours, increased dose used in severe infections Acute cough [if systemically very unwell or at higher risk of complications] ▶BY MOUTH ▶Child 1–11 months: 125 mg 3 times a day for 5 days ▶Child 1–4 years: 250 mg 3 times a day for 5 days ▶Child 5–17 years: 500 mg 3 times a day for 5 days ▶Adult: 500 mg 3 times a day for 5 days Acute otitis media ▶BY MOUTH ▶Child 1–11 months: 125 mg 3 times a day for 5–7 days ▶Child 1–4 years: 250 mg 3 times a day for 5–7 days ▶Child 5–17 years: 500 mg 3 times a day for 5–7 days Lyme disease [erythema migrans and/or non-focal symptoms] | Lyme disease [affecting cranial nerves or peripheral nervous system] ▶BY MOUTH ▶Adult: 1 g 3 times a day for 21 days Lyme arthritis | Acrodermatitis chronica atrophicans ▶BY MOUTH ▶Adult: 1 g 3 times a day for 28 days Anthrax (treatment and post-exposure prophylaxis) ▶BY MOUTH ▶Adult: 500 mg 3 times a day Dental abscess (short course) ▶BY MOUTH ▶Adult: 3 g, then 3 g after 8 hours Listerial meningitis (in combination with another antibiotic) ▶BY INTRAVENOUS INFUSION ▶Adult: 2 g every 4 hours Endocarditis (in combination with another antibiotic if necessary) ▶BY INTRAVENOUS INFUSION ▶Adult: 2 g every 4 hours Helicobacter pylori eradication [in combination with other drugs (see Helicobacter pylori infection p. 89)] ▶BY MOUTH ▶Adult: 1 g twice daily for 7 days for ﬁrst- and second- line eradication therapy; 10 days for third-line eradication therapy Acute diverticulitis [in combination with gentamicin and metronidazole] ▶BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION ▶Adult: 500 mg every 8 hours; increased if necessary to 1 g every 6 hours, increased dose used in severe infections Prophylaxis of recurrent urinary-tract infection ▶BY MOUTH ▶Adult: 250 mg once daily, dose to be taken at night, alternatively 500 mg for 1 dose, following exposure to a trigger Lower urinary-tract infection in pregnancy ▶BY MOUTH ▶Adult: 500 mg 3 times a day for 7 days Lower urinary-tract infection ▶BY MOUTH ▶Child 3–11 months: 125 mg 3 times a day for 3 days ▶Child 1–4 years: 250 mg 3 times a day for 3 days ▶Child 5–15 years: 500 mg 3 times a day for 3 days Urinary-tract infections (short course) ▶BY MOUTH ▶Adult: 3 g, then 3 g after 10–12 hours Asymptomatic bacteriuria in pregnancy ▶BY MOUTH ▶Adult: 250–500 mg 3 times a day, alternatively 750–1000 mg twice daily Urinary-tract infection (catheter-associated) ▶BY MOUTH ▶Child 16–17 years: 500 mg 3 times a day for 7 days ▶Adult: 500 mg 3 times a day for 7 days l UNLICENSED USE Amoxicillin doses in BNF Publications may differ from those in product literature. g Duration of treatment for acute otitis media differs from product literature and adheres to national guidelines. h g Amoxicillin is used for the treatment of acute exacerbation of bronchiectasis, h but is not licensed for this indication. g Amoxicillin is used for prophylaxis of recurrent urinary-tract infection, h but is not licensed for this indication. g Combination regimens and durations for Helicobacter pylori eradication may differ from product literature but adhere to national guidelines. h

Source pages 601, 602

Cautions

GENERAL CAUTIONS Acute lymphocytic leukaemia (increased risk of erythematous rashes). chronic lymphocytic leukaemia (increased risk of erythematous rashes). cytomegalovirus infection (increased risk of erythematous rashes). glandular fever (erythematous rashes common). maintain adequate hydration with high doses (particularly during parenteral therapy) SPECIFIC CAUTIONS ▶With intravenous use accumulation of sodium can occur with high parenteral doses

Source page 602

Prescribing And Dispensing Information

For choice of antibacterial therapy, see Anthrax p. 609, Cardiovascular system infections, antibacterial therapy p. 532, Central nervous system infections, antibacterial therapy p. 533, Ear infections, antibacterial therapy p. 534, Gastro-intestinal system infections, antibacterial therapy p. 535, Helicobacter pylori infection p. 89, Lyme disease p. 611, Nose infections, antibacterial therapy p. 536, Oral bacterial infections p. 537, Respiratory system infections, antibacterial therapy p. 538, Urinary-tract infections p. 622. ▶In children For choice of antibacterial therapy, see Antibacterials, use for prophylaxis p. 529.

Source page 603

Safety

Extracted information for Amoxicillin only.

Interactions

→Appendix 1: penicillins

Source page 602

Side Effects

GENERAL SIDE-EFFECTS ▶Rare or very rare Colitis haemorrhagic. crystalluria. dizziness. hyperkinesia. hypersensitivity vasculitis. mucocutaneous candidiasis. neutropenia ▶Frequency not known Jarisch-Herxheimer reaction SPECIFIC SIDE-EFFECTS ▶Rare or very rare ▶With oral use Black hairy tongue

Source page 602

Pregnancy

Not known to be harmful.

Source page 602

Breast Feeding

Trace amount in milk, but appropriate to use.

Source page 602

Hepatic Impairment

Manufacturer advises caution.

Source page 603

Renal Impairment

Risk of crystalluria with high doses (particularly during parenteral therapy). ▶With intravenous use Accumulation of sodium from injection can occur in patients with renal failure. Dose adjustments Reduce dose in severe impairment; rashes more common.

Source page 603

Dose and formulations

Extracted information for Amoxicillin only.

Directions For Administration

▶With intravenous use in adults For intravenous infusion (Amoxil ®), give intermittently in Glucose 5% or Sodium chloride 0.9%. Reconstituted solutions diluted and given without delay; suggested volume 100 mL given over 30–60 minutes or give via drip tubing in Glucose 5% or Sodium chloride 0.9%; continuous infusion not usually recommended.

Source page 603

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Powder for solution for injection ELECTROLYTES: May contain Sodium ▶Amoxicillin (Non-proprietary) Amoxicillin (as Amoxicillin sodium) 250 mg Amoxicillin 250mg powder for solution for injection vials | 10 vial P £4.80 | 10 vial P £4.50 (Hospital only) Amoxicillin (as Amoxicillin sodium) 500 mg Amoxicillin 500mg powder for solution for injection vials | 10 vial P £9.60 DT = £5.48 | 10 vial P £12.00 DT = £5.48 (Hospital only) Amoxicillin (as Amoxicillin sodium) 1 gram Amoxicillin 1g powder for solution for injection vials | 1 vial P £1.92 | 10 vial P £16.50 DT = £10.96 (Hospital only) ▶Amoxil (GlaxoSmithKline UK Ltd) Amoxicillin (as Amoxicillin sodium) 500 mg Amoxil 500mg powder for solution for injection vials | 10 vial P £5.48 DT = £5.48 Amoxicillin (as Amoxicillin sodium) 1 gram Amoxil 1g powder for solution for injection vials | 10 vial P £10.96 DT = £10.96 Oral suspension CAUTIONARY AND ADVISORY LABELS 9 EXCIPIENTS: May contain Sucrose ▶Amoxicillin (Non-proprietary) Amoxicillin (as Amoxicillin trihydrate) 25 mg per 1 ml Amoxicillin 125mg/5ml oral suspension sugar-free | 100 ml P £25.00 DT = £1.40 Amoxicillin 125mg/5ml oral suspension | 100 ml P £25.00 DT = £1.74 Amoxicillin (as Amoxicillin trihydrate) 50 mg per 1 ml Amoxicillin 250mg/5ml oral suspension sugar-free | 100 ml P £35.00 DT = £1.65 Amoxicillin 250mg/5ml oral suspension | 100 ml P £35.00 DT = £1.93 ▶Amoxil (GlaxoSmithKline UK Ltd) Amoxicillin (as Amoxicillin trihydrate) 100 mg per 1 ml Amoxil 125mg/1.25ml paediatric oral suspension | 20 ml P £3.18 DT = £3.18 Powder CAUTIONARY AND ADVISORY LABELS 9, 13 ▶Amoxicillin (Non-proprietary) Amoxicillin (as Amoxicillin trihydrate) 3 gram Amoxicillin 3g oral powder sachets sugar-free | 2 sachet P £15.00 DT = £10.36 Infection Capsule CAUTIONARY AND ADVISORY LABELS 9 ▶Amoxicillin (Non-proprietary) Amoxicillin (as Amoxicillin trihydrate) 250 mg Amoxicillin 250mg capsules | 15 capsule P £5.00 DT = £1.02 | 21 capsule P £8.99 DT = £1.43 | 500 capsule P £31.00–£120.00 Amoxicillin (as Amoxicillin trihydrate) 500 mg Amoxicillin 500mg capsules | 15 capsule P £7.50 DT = £1.12 | 21 capsule P £15.00 DT = £1.57 | 100 capsule P £7.00–£75.00 Combinations available: Co-amoxiclav, p. 582 eiiii F 575

Source page 603

Clinical care

Extracted information for Amoxicillin only.

Patient And Carer Advice

Patient counselling is advised for Amoxicillin (Amoxil ®) paediatric suspension (use of pipette). Medicines for Children leaflet: Amoxicillin for bacterial infections www.medicinesforchildren.org.uk/amoxicillin-bacterial- infections-0 l PROFESSION SPECIFIC INFORMATION Dental practitioners’ formulary Amoxicillin capsules may be prescribed. Amoxicillin sachets may be prescribed as Amoxicillin Oral Powder. Amoxicillin Oral Suspension may be prescribed.

Source page 603

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased if necessary to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased to 1 g every

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days, increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased to 1 g every

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g 3 times a day for 21 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g 3 times a day for 28 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

3 g, then 3 g after 8 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

2 g every 4 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

2 g every 4 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g twice daily for 7 days for ﬁrst- and second-

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours; increased if necessary to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

250 mg once daily, dose to be taken at night,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

3 g, then 3 g after 10–12 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

250–500 mg 3 times a day, alternatively

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

amoxicillin

Reference monograph

Part of registered formulation

AMOXYCILLIN

Reference record: Amoxicillin
Source: BNF 80 (2020–2021)
Printed source pages: 601, 602, 603
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Amoxicillin only.

Indications And Dose

Source pages 601, 602

Cautions

Source page 602

Prescribing And Dispensing Information

Source page 603

Safety

Extracted information for Amoxicillin only.

Interactions

→Appendix 1: penicillins

Source page 602

Side Effects

Source page 602

Pregnancy

Not known to be harmful.

Source page 602

Breast Feeding

Trace amount in milk, but appropriate to use.

Source page 602

Hepatic Impairment

Manufacturer advises caution.

Source page 603

Renal Impairment

Source page 603

Dose and formulations

Extracted information for Amoxicillin only.

Directions For Administration

Source page 603

Medicinal Forms

Source page 603

Clinical care

Extracted information for Amoxicillin only.

Patient And Carer Advice

Source page 603

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased if necessary to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased to 1 g every

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 601

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days;

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days; increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7–14 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days, increased if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours, increased to 1 g every

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 5–7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g 3 times a day for 21 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g 3 times a day for 28 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

3 g, then 3 g after 8 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

2 g every 4 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

2 g every 4 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

1 g twice daily for 7 days for ﬁrst- and second-

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg every 8 hours; increased if necessary to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

250 mg once daily, dose to be taken at night,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

125 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

250 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

3 g, then 3 g after 10–12 hours

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

250–500 mg 3 times a day, alternatively

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Children

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Adults

First line only; read the complete Indications and dose section above.

500 mg 3 times a day for 7 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 602

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.