Individual generic drug information

atenolol

Reference monograph

Part of registered formulation

ATENOLOL

Reference record: Atenolol
Source: BNF 80 (2020–2021)
Printed source pages: 186
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Atenolol only.

Indications And Dose

Hypertension ▶BY MOUTH ▶Adult: 25–50 mg daily, higher doses are rarely necessary Angina ▶BY MOUTH ▶Adult: 100 mg daily in 1–2 divided doses Arrhythmias ▶BY MOUTH ▶Adult: 50–100 mg daily ▶BY INTRAVENOUS INJECTION ▶Adult: 2.5 mg every 5 minutes if required, to be given at a rate of 1 mg/minute, treatment course may be repeated every 12 hours if required; maximum 10 mg per course ▶BY INTRAVENOUS INFUSION ▶Adult: 150 micrograms/kg every 12 hours if required, to be given over 20 minutes Migraine prophylaxis ▶BY MOUTH ▶Adult: 50–200 mg daily in divided doses Early intervention within 12 hours of myocardial infarction ▶INITIALLY BY INTRAVENOUS INJECTION ▶Adult: 5–10 mg, to be given at a rate of 1 mg/minute, followed by (by mouth) 50 mg after 15 minutes, then (by mouth) 50 mg after 12 hours, then (by mouth) 100 mg after 12 hours, then (by mouth) 100 mg once daily l UNLICENSED USE Use of atenolol for migraine prophylaxis is an unlicensed indication.

Source page 186

Safety

Extracted information for Atenolol only.

Important Safety Information

SAFE PRACTICE Atenolol has been confused with amlodipine; care must be taken to ensure the correct drug is prescribed and dispensed.

Source page 186

Interactions

→Appendix 1: beta blockers, selective

Source page 186

Side Effects

▶Common or very common Gastrointestinal disorder ▶Rare or very rare Alopecia. dry mouth. hepatic disorders. mood altered. postural hypotension. psychosis. skin reactions. thrombocytopenia ▶Frequency not known Hypersensitivity. lupus-like syndrome

Source page 186

Breast Feeding

Water soluble beta-blockers such as atenolol are present in breast milk in greater amounts than other beta blockers.

Source page 186

Renal Impairment

Dose adjustments ▶With oral use Max. 50 mg daily if eGFR 15–35 mL/minute/1.73 m2; max. 25 mg daily or 50 mg on alternate days if eGFR less than 15 mL/minute/1.73 m2. ▶With intravenous use Max. 10 mg on alternate days if eGFR 15–35 mL/minute/1.73 m2; max.10 mg every 4 days if eGFR less than 15 mL/minute/1.73 m2.

Source page 186

Dose and formulations

Extracted information for Atenolol only.

Directions For Administration

For intravenous infusion (Tenormin ®), give intermittently in Glucose 5% or Sodium chloride 0.9%. Suggested infusion time 20 minutes.

Source page 186

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Forms available from special-order manufacturers include: oral suspension, oral solution Solution for injection ▶Tenormin (AstraZeneca UK Ltd) Atenolol 500 microgram per 1 ml Tenormin 5mg/10ml solution for injection ampoules | 10 ampoule P £34.45 (Hospital only) Oral solution CAUTIONARY AND ADVISORY LABELS 8 ▶Atenolol (Non-proprietary) Atenolol 5 mg per 1 ml Atenolol 25mg/5ml oral solution sugar-free | 300 ml P £73.00 DT = £5.60 Tablet CAUTIONARY AND ADVISORY LABELS 8 ▶Atenolol (Non-proprietary) Atenolol 25 mg Atenolol 25mg tablets | 28 tablet P £1.39 DT = £0.71 Atenolol 50 mg Atenolol 50mg tablets | 28 tablet P £4.09 DT = £0.75 Atenolol 100 mg Atenolol 100mg tablets | 28 tablet P £5.19 DT = £0.84 ▶Tenormin (AstraZeneca UK Ltd) Atenolol 50 mg Tenormin LS 50mg tablets | 28 tablet P £10.22 DT = £0.75

Source page 186

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

25–50 mg daily, higher doses are rarely

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

100 mg daily in 1–2 divided doses

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

50–100 mg daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

2.5 mg every 5 minutes if required, to be given at

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

150 micrograms/kg every 12 hours if required, to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

50–200 mg daily in divided doses

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

5–10 mg, to be given at a rate of 1 mg/minute,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

atenolol

Reference monograph

Part of registered formulation

ATENOLOL

Reference record: Atenolol
Source: BNF 80 (2020–2021)
Printed source pages: 186
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Atenolol only.

Indications And Dose

Source page 186

Safety

Extracted information for Atenolol only.

Important Safety Information

SAFE PRACTICE Atenolol has been confused with amlodipine; care must be taken to ensure the correct drug is prescribed and dispensed.

Source page 186

Interactions

→Appendix 1: beta blockers, selective

Source page 186

Side Effects

Source page 186

Breast Feeding

Water soluble beta-blockers such as atenolol are present in breast milk in greater amounts than other beta blockers.

Source page 186

Renal Impairment

Source page 186

Dose and formulations

Extracted information for Atenolol only.

Directions For Administration

For intravenous infusion (Tenormin ®), give intermittently in Glucose 5% or Sodium chloride 0.9%. Suggested infusion time 20 minutes.

Source page 186

Medicinal Forms

Source page 186

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

25–50 mg daily, higher doses are rarely

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

100 mg daily in 1–2 divided doses

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

50–100 mg daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

2.5 mg every 5 minutes if required, to be given at

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

150 micrograms/kg every 12 hours if required, to

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

50–200 mg daily in divided doses

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Adults

First line only; read the complete Indications and dose section above.

5–10 mg, to be given at a rate of 1 mg/minute,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 186

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.