Therapeutic Action
Sulfone antibacterial, antileprotic
Source page 106
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Individual generic drug information
Extracted information for DAPSONE only.
Sulfone antibacterial, antileprotic
Source page 106
Prophylaxis of toxoplasmosis and pneumocystosis, in combination with pyrimethamine and folinic acid Treatment of pneumocystosis, in combination with trimethoprim Paucibacillary and multibacillary leprosy, in combination with rifampicin and clofazimine
Source page 106
Extracted information for DAPSONE only.
Do not administer to patients with allergy to sulfones or severe anaemia (first treat anaemia). Administer with caution to patients with renal or hepatic impairment. May cause: haemolytic anaemia in patients with G6PD deficiency, dose-related haemolytic anaemia, neutropenia, methaemoglobinaemia, pruritus, rash, gastrointestinal disturbances, peripheral neuropathies, agranulocytosis; hypersensitivity reactions during the first month of treatment (fever, jaundice, hepatitis, adenopathy, exfoliative dermatitis, etc.) requiring permanent discontinuation of treatment. Monitor blood count and transaminases if possible. Monitor combination with zidovudine (increased haematological toxicity). Pregnancy: no contra-indication Breast-feeding: no contra-indication
Source page 107
Extracted information for DAPSONE only.
50 mg and 100 mg tablets
Source page 106
Prophylaxis of pneumocystosis only Child: 2 mg/kg once daily (max. 100 mg daily) Adult: 100 mg once daily Prophylaxis of toxoplasmosis and pneumocystosis Child: 2 mg/kg once daily (max. 25 mg daily) Adult: 200 mg once weekly or 50 mg once daily Treatment of pneumocystosis Child: 2 mg/kg once daily (max. 100 mg daily) Adult: 100 mg once daily Paucibacillary and multibacillary leprosy Child under 10 years: 2 mg/kg once daily Child from 10 to 14 years: 50 mg once daily Child 15 years and over and adult: 100 mg once daily
Source page 106
Prophylaxis of toxoplasmosis and pneumocystosis: as long as necessary Treatment of pneumocystosis: 21 days Paucibacillary leprosy: 6 months Multibacillary leprosy: 12 months
Source page 107
Extracted information for DAPSONE only.
– – Below 25 °C
Source page 107
Filter the extracted dose blocks for this individual drug.
2 mg/kg once daily (max. 100 mg daily)
Candidate age grouping · source page 106
100 mg once daily
Candidate age grouping · source page 106
2 mg/kg once daily (max. 25 mg daily)
Candidate age grouping · source page 106
200 mg once weekly or 50 mg once daily
Candidate age grouping · source page 106
2 mg/kg once daily (max. 100 mg daily)
Candidate age grouping · source page 106
100 mg once daily
Candidate age grouping · source page 106
2 mg/kg once daily
Candidate age grouping · source page 106
50 mg once daily
Candidate age grouping · source page 106
100 mg once daily
Candidate age grouping · source page 106