Individual generic drug information
Extracted information for Desloratadine only.
Symptomatic relief of allergy such as allergic rhinitis, urticaria, chronic idiopathic urticaria ▶BY MOUTH ▶Child 1–5 years: 1.25 mg once daily ▶Child 6–11 years: 2.5 mg once daily ▶Child 12–17 years: 5 mg once daily ▶Adult: 5 mg once daily
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▶Desloratadine is a metabolite of loratadine.
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Contra-indicated if history of hypersensitivity to loratadine.
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Flavours of oral liquid formulations may include bubblegum.
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Extracted information for Desloratadine only.
→Appendix 1: antihistamines, non- sedating
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▶Common or very common Asthenia. dry mouth. headache ▶Rare or very rare Akathisia. arrhythmias. diarrhoea. dizziness. drowsiness. gastrointestinal discomfort. hallucination. hepatic disorders. insomnia. myalgia. nausea. palpitations. seizure. vomiting ▶Frequency not known Behaviour abnormal. photosensitivity reaction. QT interval prolongation SIDE-EFFECTS, FURTHER INFORMATION Non-sedating antihistamines such as desloratadine cause less sedation and psychomotor impairment than the older antihistamines, but can still occur; sedation is generally minimal. This is because non-sedating antihistamines penetrate the blood brain barrier to a much lesser extent.
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Most manufacturers of antihistamines advise avoiding their use during pregnancy; however, there is no evidence of teratogenicity.
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Most antihistamines are present in breast milk in varying amounts; although not known to be harmful, most manufacturers advise avoiding their use in mothers who are breast-feeding.
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Use with caution in severe impairment.
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Extracted information for Desloratadine only.
There can be variation in the licensing of different medicines containing the same drug. Oral solution EXCIPIENTS: May contain Propylene glycol, sorbitol ▶Desloratadine (Non-proprietary) Desloratadine 500 microgram per 1 ml Desloratadine 2.5mg/5ml oral solution sugar-free | 100 ml P £6.57 sugar-free | 150 ml P £8.12–£9.86 DT = £9.86 ▶Neoclarityn (Merck Sharp & Dohme Ltd) Desloratadine 500 microgram per 1 ml Neoclarityn 2.5mg/5ml oral solution sugar-free | 100 ml P £6.77 sugar-free | 150 ml P £10.15 DT = £9.86 Tablet ▶Desloratadine (Non-proprietary) Desloratadine 5 mg Desloratadine 5mg tablets | 30 tablet P £6.77 DT = £1.32 ▶Neoclarityn (Merck Sharp & Dohme Ltd) Desloratadine 5 mg Neoclarityn 5mg tablets | 30 tablet P £6.77 DT = £1.32
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Extracted information for Desloratadine only.
Driving and skilled tasks Although drowsiness is rare, nevertheless patients should be advised that it can occur and may affect performance of skilled tasks (e.g. cycling or driving); excess alcohol should be avoided.
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Filter the extracted dose blocks for this individual drug.
First line only; read the complete Indications and dose section above.
1.25 mg once daily
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 316
First line only; read the complete Indications and dose section above.
2.5 mg once daily
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 316
First line only; read the complete Indications and dose section above.
5 mg once daily
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 316
First line only; read the complete Indications and dose section above.
5 mg once daily
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 316
