Therapeutic Action
Anxiolytic, sedative, antiseizure (anticonvulsant), muscle relaxant
Source page 114
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Individual generic drug information
Extracted information for DIAZEPAM only.
Anxiolytic, sedative, antiseizure (anticonvulsant), muscle relaxant
Source page 114
Severe anxiety, insomnia, and agitation
Source page 114
Extracted information for DIAZEPAM only.
Do not administer to patients with severe respiratory insufficiency, severe hepatic impairment or acute alcohol intoxication. Administer with caution: to older patients and patients with renal or hepatic impairment (reduce the dose by half); to patients with history of drug/substance abuse or mental health disorders. May cause: hypotension, muscle weakness, ataxia, hypotonia, drowsiness (caution when driving/operating machinery), lethargy, confusion, impaired concentration, memory loss, hyperactive or aggressive behaviour; withdrawal syndrome or rebound effect if prolonged treatment is discontinued abruptly; respiratory depression and coma in the event of overdose. Avoid or monitor in combination with: drugs containing alcohol, opioid analgesics, antipsychotics, first-generation antihistamines (hydroxyzine, promethazine), antidepressants, other antiseizure medications, etc. (increased sedation); enzyme inducers such as rifampicin, rifabutin, nevirapine, phenobarbital, phenytoin, carbamazepine, etc. (reduced effect of diazepam); omeprazole, macrolides, ritonavir, isoniazid, fluconazole, itraconazole, etc. (increased diazepam toxicity); phenytoin (increased phenytoin toxicity). Avoid alcohol during treatment (increased risk of adverse effects). Pregnancy and breast-feeding: avoid (passage through the placenta and breast milk)
Source pages 114, 115
Extracted information for DIAZEPAM only.
2 mg and 5 mg tablets
Source page 114
Anxiety Adult: 2.5 to 5 mg 2 times daily for 2 to 3 weeks max. reducing the dose by half the last days before stopping treatment Insomnia Adult: 2 to 5 mg once daily at bedtime for 7 days max. Agitation Adult: 10 mg single dose
Source page 114
Extracted information for DIAZEPAM only.
Diazepam is subject to international controls: follow national regulations. Diazepam is also used in the treatment of pre-delirium tremens (alcohol withdrawal) in adults: 10 mg every 6 hours for 1 to 3 days, then reduce and stop over 7 days.
Source page 115
– – Below 25 °C
Source page 115
Filter the extracted dose blocks for this individual drug.
2.5 to 5 mg 2 times daily for 2 to 3 weeks max. reducing the dose by half the last days before stopping treatment
Candidate age grouping · source page 114
2 to 5 mg once daily at bedtime for 7 days max.
Candidate age grouping · source page 114
10 mg single dose
Candidate age grouping · source page 114