Drug Action
Elvitegravir is an inhibitor of HIV integrase, which is an enzyme required for viral replication.
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Individual generic drug information
Extracted information for Elvitegravir only.
Elvitegravir is an inhibitor of HIV integrase, which is an enzyme required for viral replication.
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HIV infection without resistance to other inhibitors of HIV integrase, in combination with low-dose ritonavir and atazanavir or lopinavir ▶BY MOUTH ▶Adult: 85 mg once daily, take at the same time as a once daily ritonavir-boosted regimen or with the first dose of a twice daily ritonavir-boosted regimen HIV infection without resistance to other inhibitors of HIV integrase, in combination with low-dose ritonavir and darunavir or fosamprenavir ▶BY MOUTH ▶Adult: 150 mg once daily, take with the first dose of a twice daily ritonavir-boosted regimen
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Elderly—limited information available
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Extracted information for Elvitegravir only.
→Appendix 1: elvitegravir
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▶Common or very common Diarrhoea. fatigue. headache. nausea. rash. vomiting ▶Uncommon Depression. dizziness. drowsiness. flatulence . gastrointestinal discomfort. insomnia. paraesthesia. suicidal ideation (in patients with history of depression or psychiatric illness). taste altered ▶Frequency not known Hyperglycaemia. osteonecrosis. weight increased
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Manufacturer advises women of child-bearing potential should use effective contraception during treatment (if using a hormonal contraceptive, it must contain norgestimate as the progestogen and at least 30 micrograms ethinylestradiol).
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Manufacturer advises avoid unless essential—limited data available.
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Extracted information for Elvitegravir only.
No licensed medicines listed. Combinations available: Elvitegravir with cobicistat, emtricitabine and tenofovir alafenamide, p. 686. Elvitegravir with cobicistat, emtricitabine and tenofovir disoproxil, p. 686
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Extracted information for Elvitegravir only.
Missed doses Manufacturer advises if a dose is more than 18 hours late, the missed dose should not be taken and the next dose should be taken at the normal time. If vomiting occurs within 1 hour of taking a dose, a replacement dose should be taken.
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Filter the extracted dose blocks for this individual drug.
First line only; read the complete Indications and dose section above.
85 mg once daily, take at the same time as a
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 702
First line only; read the complete Indications and dose section above.
150 mg once daily, take with the first dose of a
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 702