Individual generic drug information

ketoconazole

Reference monograph

Part of registered formulation

KETOCONAZOLE + ZINC PYRITHIONE

Reference record: Ketoconazole
Source: BNF 80 (2020–2021)
Printed source pages: 1320, 1321
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Ketoconazole only.

Indications And Dose

Tinea pedis ▶TO THE SKIN USING CREAM ▶Adult: Apply twice daily Fungal skin infection (not Tinea pedis) ▶TO THE SKIN USING CREAM ▶Adult: Apply 1–2 times a day Treatment of seborrhoeic dermatitis and dandruff ▶TO THE SKIN USING SHAMPOO ▶Child 12–17 years: Apply twice weekly for 2–4 weeks, leave preparation on for 3–5 minutes before rinsing ▶Adult: Apply twice weekly for 2–4 weeks, leave preparation on for 3–5 minutes before rinsing Prophylaxis of seborrhoeic dermatitis and dandruff ▶TO THE SKIN USING SHAMPOO ▶Child 12–17 years: Apply every 1–2 weeks, leave preparation on for 3–5 minutes before rinsing ▶Adult: Apply every 1–2 weeks, leave preparation on for 3–5 minutes before rinsing Treatment of pityriasis versicolor ▶TO THE SKIN USING SHAMPOO ▶Child 12–17 years: Apply once daily for maximum 5 days, leave preparation on for 3–5 minutes before rinsing ▶Adult: Apply once daily for maximum 5 days, leave preparation on for 3–5 minutes before rinsing Prophylaxis of pityriasis versicolor ▶TO THE SKIN USING SHAMPOO ▶Child 12–17 years: Apply once daily for up to 3 days before sun exposure, leave preparation on for 3–5 minutes before rinsing ▶Adult: Apply once daily for up to 3 days before sun exposure, leave preparation on for 3–5 minutes before rinsing

Source page 1320

Contra Indications

Acute porphyrias p. 1120

Source page 1320

Cautions

Avoid contact with eyes. avoid contact with mucous membranes

Source page 1320

National Funding Access Decisions

NHS restrictions Nizoral ® cream is not prescribable in NHS primary care except for the treatment of seborrhoeic dermatitis and pityriasis versicolor; endorse prescription ’SLS’.

Source page 1320

Exceptions To Legal Category

A 15-g tube is available for sale to the public for the treatment of tinea pedis, tinea cruris, and candidal intertrigo. Can be sold to the public for the prevention and treatment of dandruff and seborrhoeic dermatitis of the scalp as a shampoo formulation containing ketoconazole maximum 2%, in a pack containing maximum 120 mL and labelled to show a maximum frequency of application of once every 3 days.

Source page 1320

Safety

Extracted information for Ketoconazole only.

Interactions

→Appendix 1: antifungals, azoles

Source page 1320

Side Effects

▶Common or very common Skin reactions ▶Uncommon Alopecia. angioedema. excessive tearing. folliculitis. hair changes ▶Rare or very rare Eye irritation. taste altered

Source page 1320

Dose and formulations

Extracted information for Ketoconazole only.

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Cream EXCIPIENTS: May contain Cetostearyl alcohol (including cetyl and stearyl alcohol), polysorbates, propylene glycol ▶Nizoral (Janssen-Cilag Ltd) Ketoconazole 20 mg per 1 gram Nizoral 2% cream | 30 gram P £4.24 DT = £4.24 Shampoo EXCIPIENTS: May contain Imidurea ▶Ketoconazole (Non-proprietary) Ketoconazole 20 mg per 1 gram Ketoconazole 2% shampoo | 120 ml P £4.81 DT = £4.53 ▶Dandrazol (Transdermal Ltd) Ketoconazole 20 mg per 1 gram Dandrazol 2% shampoo | 120 ml P £3.39 DT = £4.53 ▶Nizoral (Thornton & Ross Ltd) Ketoconazole 20 mg per 1 gram Nizoral 2% shampoo | 120 ml P £3.59 DT = £4.53

Source page 1321

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Apply twice daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply 1–2 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply twice weekly for 2–4 weeks,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply twice weekly for 2–4 weeks, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply every 1–2 weeks, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply every 1–2 weeks, leave preparation on for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply once daily for maximum 5 days,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply once daily for maximum 5 days, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply once daily for up to 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply once daily for up to 3 days before sun

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

ketoconazole

Reference monograph

Part of registered formulation

KETOCONAZOLE + ZINC PYRITHIONE

Reference record: Ketoconazole
Source: BNF 80 (2020–2021)
Printed source pages: 1320, 1321
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Ketoconazole only.

Indications And Dose

Source page 1320

Contra Indications

Acute porphyrias p. 1120

Source page 1320

Cautions

Avoid contact with eyes. avoid contact with mucous membranes

Source page 1320

National Funding Access Decisions

NHS restrictions Nizoral ® cream is not prescribable in NHS primary care except for the treatment of seborrhoeic dermatitis and pityriasis versicolor; endorse prescription ’SLS’.

Source page 1320

Exceptions To Legal Category

Source page 1320

Safety

Extracted information for Ketoconazole only.

Interactions

→Appendix 1: antifungals, azoles

Source page 1320

Side Effects

▶Common or very common Skin reactions ▶Uncommon Alopecia. angioedema. excessive tearing. folliculitis. hair changes ▶Rare or very rare Eye irritation. taste altered

Source page 1320

Dose and formulations

Extracted information for Ketoconazole only.

Medicinal Forms

Source page 1321

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

Apply twice daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply 1–2 times a day

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply twice weekly for 2–4 weeks,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply twice weekly for 2–4 weeks, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply every 1–2 weeks, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply every 1–2 weeks, leave preparation on for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply once daily for maximum 5 days,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply once daily for maximum 5 days, leave

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Children

First line only; read the complete Indications and dose section above.

Apply once daily for up to 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Adults

First line only; read the complete Indications and dose section above.

Apply once daily for up to 3 days before sun

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1320

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.