Therapeutic Action
Antiretroviral, HIV protease inhibitor
Source page 285
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Individual generic drug information
Extracted information for RITONAVIR only.
Antiretroviral, HIV protease inhibitor
Source page 285
Booster for protease inhibitors (atazanavir, darunavir, lopinavir, etc.) in HIV infection. Ritonavir should not be used alone.
Source page 285
Extracted information for RITONAVIR only.
Do not administer to patients with severe hepatic impairment. Administer with caution and monitor use in patients with haemophilia (increased bleeding) or mild to moderate hepatic impairment. The adverse effects of ritonavir as a booster are also dependent on the boosted protease inhibitor. May cause: gastrointestinal disturbances, fatigue, headache, dizziness, paraesthesia, joint and muscle pain, taste disturbances, hyperglycaemia, hyperlipidaemia, lipodystrophy, conduction disorders; pancreatitis, hepatic disorders, skin rash sometimes severe; in this event, stop treatment immediately. Ritonavir reduces the efficacy of implants and oral contraceptives.: use injectable medroxyprogesterone or an intrauterine device. Only when combined with atazanavir, an oral contraceptive containing at least 30 micrograms of ethinylestradiol per tablet may also be used. Pregnancy: no contra-indication
Source pages 285, 286
Extracted information for RITONAVIR only.
25 mg and 100 mg tablets
Source page 285
Dosage depends on the administration schedule of the boosted protease inhibitor. The daily dose is administered once daily or in 2 divided doses. Child 14 to < 25 kg: 50 mg (two 25 mg tablets) 2 times daily, or 100 mg (four 25 mg tablets or one 100 mg tablet) once daily Child ≥ 25 kg and adult: 100 mg (one 100 mg tablet) once or 2 times daily
Source page 285
Depending on the efficacy and tolerance of the boosted protease inhibitor and ritonavir.
Source page 285
Extracted information for RITONAVIR only.
Take with meals. Tablets are not recommended in children < 14 kg. Also comes in fixed-dose combinations with other protease inhibitors (atazanavir, darunavir, lopinavir, etc.). Preferably use these formulations when available.
Source page 286
– – Below 25 °C
Source page 286
Filter the extracted dose blocks for this individual drug.
100 mg (one 100 mg tablet) once or 2 times daily
Candidate age grouping · source page 285