Individual generic drug information

mebendazole

Reference monograph

Part of registered formulation

MEBENDAZOLE

Reference record: Mebendazole
Source: BNF 80 (2020–2021)
Printed source pages: 662, 663
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Mebendazole only.

Indications And Dose

Threadworm infections ▶BY MOUTH ▶Child 6 months–17 years: 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks ▶Adult: 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks Whipworm infections | Hookworm infections ▶BY MOUTH ▶Child 1–17 years: 100 mg twice daily for 3 days ▶Adult: 100 mg twice daily for 3 days Roundworm infections ▶BY MOUTH ▶Child 1 year: 100 mg twice daily for 3 days ▶Child 2–17 years: 100 mg twice daily for 3 days, alternatively 500 mg for 1 dose ▶Adult: 100 mg twice daily for 3 days, alternatively 500 mg for 1 dose Threadworm infections (dose approved for use by community practitioner nurse prescribers) ▶BY MOUTH ▶Child 2–17 years: 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks ▶Adult: 100 mg for 1 dose, if reinfection occurs, second dose may be needed after 2 weeks l UNLICENSED USE Not licensed for use as a single dose of 500 mg in roundworm infections. ▶In children Not licensed for use in children under 2 years.

Source page 662

Prescribing And Dispensing Information

Flavours of oral liquid formulations may include banana.

Source page 663

Exceptions To Legal Category

Mebendazole tablets can be sold to the public if supplied for oral use in the treatment of enterobiasis in adults and children over 2 years provided its container or package is labelled to show a max. single dose of 100 mg and it is supplied in a container or package containing not more than 800 mg.

Source page 663

Safety

Extracted information for Mebendazole only.

Interactions

→Appendix 1: mebendazole

Source page 662

Side Effects

▶Common or very common Gastrointestinal discomfort ▶Uncommon Diarrhoea. ﬂatulence ▶Rare or very rare Alopecia. dizziness. hepatitis. neutropenia. seizure. severe cutaneous adverse reactions (SCARs). skin reactions

Source page 662

Pregnancy

Manufacturer advises avoid—toxicity in animal studies.

Source page 662

Breast Feeding

Amount present in milk too small to be harmful but manufacturer advises avoid.

Source page 662

Dose and formulations

Extracted information for Mebendazole only.

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Oral suspension ▶Vermox (Janssen-Cilag Ltd) Mebendazole 20 mg per 1 ml Vermox 100mg/5ml oral suspension | 30 ml P £1.55 DT = £1.55 Chewable tablet ▶Vermox (Janssen-Cilag Ltd) Mebendazole 100 mg Vermox 100mg chewable tablets sugar-free | 6 tablet P £1.34 DT = £1.34

Source page 663

Clinical care

Extracted information for Mebendazole only.

Patient And Carer Advice

Medicines for Children leaflet: Mebendazole for worm infections www.medicinesforchildren.org.uk/mebendazole-worm- infections

Source page 663

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Children

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection occurs, second

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days, alternatively

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection occurs, second

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

mebendazole

Reference monograph

Part of registered formulation

MEBENDAZOLE

Reference record: Mebendazole
Source: BNF 80 (2020–2021)
Printed source pages: 662, 663
Age groups indexed: 2

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Mebendazole only.

Indications And Dose

Source page 662

Prescribing And Dispensing Information

Flavours of oral liquid formulations may include banana.

Source page 663

Exceptions To Legal Category

Source page 663

Safety

Extracted information for Mebendazole only.

Interactions

→Appendix 1: mebendazole

Source page 662

Side Effects

Source page 662

Pregnancy

Manufacturer advises avoid—toxicity in animal studies.

Source page 662

Breast Feeding

Amount present in milk too small to be harmful but manufacturer advises avoid.

Source page 662

Dose and formulations

Extracted information for Mebendazole only.

Medicinal Forms

Source page 663

Clinical care

Extracted information for Mebendazole only.

Patient And Carer Advice

Medicines for Children leaflet: Mebendazole for worm infections www.medicinesforchildren.org.uk/mebendazole-worm- infections

Source page 663

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Children

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection occurs, second

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days,

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg twice daily for 3 days, alternatively

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Children

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Adults

First line only; read the complete Indications and dose section above.

100 mg for 1 dose, if reinfection occurs, second

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 662

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.