Indications And Dose
In combination with aspirin for the prevention of atherothrombotic events in patients with acute coronary syndrome undergoing percutaneous coronary intervention ▶BY MOUTH ▶Adult 18–74 years (body-weight up to 60 kg): Initially 60 mg for 1 dose, then 5 mg once daily usually for up to 12 months ▶Adult 18–74 years (body-weight 60 kg and above): Initially 60 mg for 1 dose, then 10 mg once daily usually for up to 12 months ▶Adult 75 years and over: Initially 60 mg for 1 dose, then 5 mg once daily usually for up to 12 months Patients undergoing coronary angiography within 48 hours of admission for unstable angina or NSTEMI ▶BY MOUTH ▶Adult: Loading dose 60 mg, not to be administered until the time of percutaneous coronary intervention in order to minimise the risk of bleeding, maintenance dose of 10 mg or 5 mg daily should then be selected as appropriate based on age and weight
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