Names and pronunciation
(peer-a-zin’a-mide)
Source page 1108
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Individual generic drug information
Extracted information for pyrazinamide only.
(peer-a-zin’a-mide)
Source page 1108
Func. class.: Antitububerculotic Func. class.: Pediculicide, pyrethrin
Source pages 1108, 1109
USES: Mycobacterium tuberculosis, drug- susceptible TB as part of combination therapy (without HIV) USES: Treatment of Pediculus hum anus infestations
Source pages 1108, 1109
Extracted information for pyrazinamide only.
CONTRAINDICATIONS Hypersensitivity
Source page 1109
Extracted information for pyrazinamide only.
DOSAGE AND ROUTES • Adults > 90 kg (lean body weight): PO 15-30 mg/kg/dose once daily (max: 3 g/ day) or 50-75 mg/kg/dose twice weekly. • Adults weighing 76 to 90 kg (lean body weight): PO 2 g once daily or 5 days/wk, or alternatively, 3 g 3 days/wk or 4 g twice weekly. • Adults weighing 56 to 75 kg (lean body weight): PO 1.5 g once daily or 5 days/wk, or alternatively, 2.5 g 3 days/wk or 3 g PO twice weekly. • Infants, children, and adolescents 30-40 mg/kg/dose (lean body weight) (max: 2 g/dose): PO once daily or 5 days/wk, or alternatively, 50 mg/kg/ dose (lean body weight) 3 days/wk (max: 3 g/dose) or twice weekly (max: 4 g/dose) mo intensive phase as first-line therapy DOSAGE AND ROUTES Pediculosis capitis (head lice infes- tation)/pediculosis corporis (body lice infestation). Child: Topical: Apply to dry scalp hair or other affected areas in an amount suf- ficient to thoroughly wet the area, if treat- ing head lice, first apply behind ears and to back of neck, after 10 min, add warm water to form a good lather, wash, and thoroughly rinse with water until all lather is gone, dry hair with a clean towel and comb with a fine-tooth comb to remove any remaining nits, repeat after 7-10 days
Source pages 1108, 1109
Available forms: Tabs 500 mg (pi-reth′rinz/pye-per′ oh-nil) Lice Shampoo , RID Available forms: Shampoo 0.33%/4%
Source page 1109
Filter the extracted dose blocks for this individual drug.
• Adults > 90 kg (lean body weight): PO 15-30 mg/kg/dose once daily (max: 3 g/ day) or 50-75 mg/kg/dose twice weekly.
Candidate age grouping · source pages 1108, 1109
• Adults weighing 76 to 90 kg (lean body weight): PO 2 g once daily or 5 days/wk, or alternatively, 3 g 3 days/wk or 4 g twice weekly.
Candidate age grouping · source pages 1108, 1109
• Adults weighing 56 to 75 kg (lean body weight): PO 1.5 g once daily or 5 days/wk, or alternatively, 2.5 g 3 days/wk or 3 g PO twice weekly.
Candidate age grouping · source pages 1108, 1109
• Infants, children, and adolescents 30-40 mg/kg/dose (lean body weight) (max: 2 g/dose): PO once daily or 5 days/wk, or alternatively, 50 mg/kg/ dose (lean body weight) 3 days/wk (max: 3 g/dose) or twice weekly (max: 4 g/dose) mo intensive phase as first-line therapy DOSAGE AND ROUTES Pediculosis capitis (head lice infes- tation)/pediculosis corporis (body lice infestation). Child: Topical: Apply to dry scalp hair or other affected areas in an amount suf- ficient to thoroughly wet the area, if treat- ing head lice, first apply behind ears and to back of neck, after 10 min, add warm water to form a good lather, wash, and thoroughly rinse with water until all lather is gone, dry hair with a clean towel and comb with a fine-tooth comb to remove any remaining nits, repeat after 7-10 days
Candidate age grouping · source pages 1108, 1109