Therapeutic Action
Antibacterial (group of aminoglycosides)
Source page 489
Loading InternPractice…
Individual generic drug information
Extracted information for STREPTOMYCIN only.
Antibacterial (group of aminoglycosides)
Source page 489
Alternative to gentamicin in plague Brucellosis, in combination with doxycycline
Source page 489
Extracted information for STREPTOMYCIN only.
Do not administer in patients with allergy to aminoglycosides. Administer with caution to patients with history of renal, vestibular or auditory problems. Reduce the dose in patients with renal impairment. May cause: irreversible ototoxicity (vestibular and auditory damage), nephrotoxicity, neuropathy, paraesthesia, neuromuscular blockade; rarely, allergic reactions. Stop treatment in the event of dizziness, tinnitus or hearing loss (ototoxicity). Drink sufficient liquid to limit the risk of renal toxicity. Do not combine with another aminoglycoside. Avoid or monitor combination with: furosemide, amphotericin B, vancomycin (enhanced renal and/or auditory toxicity); neuromuscular blockers (increased neuromuscular blockage). Pregnancy: CONTRA-INDICATED Breast-feeding: no contra-indication
Source pages 489, 490
Extracted information for STREPTOMYCIN only.
Powder for injection, vial containing 1 g of streptomycin base, to be dissolved in 3.2 ml of water for injection to obtain a 250 mg/ml solution, for IM injection. DO NOT ADMINISTER BY IV INJECTION.
Source page 489
Plague Child: 15 mg/kg (max. 1 g) every 12 hours Adult: 1 g every 12 hours Brucellosis Adult: 1 g once daily
Source page 489
Plague: 10 to 14 days Brucellosis: 2 weeks
Source page 489
Extracted information for STREPTOMYCIN only.
– Below 25 °C
Source page 490
Filter the extracted dose blocks for this individual drug.
15 mg/kg (max. 1 g) every 12 hours
Candidate age grouping · source page 489
1 g every 12 hours
Candidate age grouping · source page 489
1 g once daily
Candidate age grouping · source page 489