Individual generic drug information

pyrimethamine

Reference monograph

Part of registered formulation

(SULFADOXINE + PYRIMETHAMINE) + AMODIAQUINE HYDROCHLORIDE

Reference record: pyrimethamine
Source: Mosby’s 2024 Nursing Drug Reference
Printed source pages: 1112
Age groups indexed: Not recorded

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for pyrimethamine only.

Names and pronunciation

(peer-i-meth′a-meen) Daraprim

Source page 1112

Functional class

Func. class.: Antimalarial

Source page 1112

Uses

USES: Treatment of toxoplasmosis (in combination with a sulfonamide)

Source page 1112

Safety

Extracted information for pyrimethamine only.

Contraindications

CONTRAINDICATIONS Hypersensitivity to pyrimethamine or any component, megaloblastic anemia due to folate deficiency

Source page 1112

Dose and formulations

Extracted information for pyrimethamine only.

Dosage and routes

DOSAGE AND ROUTES Toxoplasmosis treatment. Adult: PO 50-75 mg/day × 1-3 wk depending then reduce dose by 50% and continue for 4-5 wk; use with a sulfonamide in combination with leucovorin

Source page 1112

Available forms

Available forms: Tabs 25 mg

Source page 1112

Dose text by age group

Filter the extracted dose blocks for this individual drug.

No dose block was identified for this age filter. This does not establish whether the drug is suitable for that age group.

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

pyrimethamine

Reference monograph

Part of registered formulation

(SULFADOXINE + PYRIMETHAMINE) + AMODIAQUINE HYDROCHLORIDE

Reference record: pyrimethamine
Source: Mosby’s 2024 Nursing Drug Reference
Printed source pages: 1112
Age groups indexed: Not recorded

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for pyrimethamine only.

Names and pronunciation

(peer-i-meth′a-meen) Daraprim

Source page 1112

Functional class

Func. class.: Antimalarial

Source page 1112

Uses

USES: Treatment of toxoplasmosis (in combination with a sulfonamide)

Source page 1112

Safety

Extracted information for pyrimethamine only.

Contraindications

CONTRAINDICATIONS Hypersensitivity to pyrimethamine or any component, megaloblastic anemia due to folate deficiency

Source page 1112

Dose and formulations

Extracted information for pyrimethamine only.

Dosage and routes

DOSAGE AND ROUTES Toxoplasmosis treatment. Adult: PO 50-75 mg/day × 1-3 wk depending then reduce dose by 50% and continue for 4-5 wk; use with a sulfonamide in combination with leucovorin

Source page 1112

Available forms

Available forms: Tabs 25 mg

Source page 1112

Dose text by age group

Filter the extracted dose blocks for this individual drug.

No dose block was identified for this age filter. This does not establish whether the drug is suitable for that age group.

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.