Individual generic drug information

tenoxicam

Reference monograph

Part of registered formulation

TENOXICAM

Reference record: Tenoxicam
Source: BNF 80 (2020–2021)
Printed source pages: 1236, 1237
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Tenoxicam only.

Indications And Dose

Pain and inflammation in rheumatic disease ▶BY MOUTH ▶Adult: 20 mg once daily ▶BY INTRAVENOUS INJECTION, OR BY INTRAMUSCULAR INJECTION ▶Adult: 20 mg once daily as initial treatment for 1–2 days if oral administration not possible Pain and inflammation in acute musculoskeletal disorders ▶BY MOUTH ▶Adult: 20 mg once daily for 7 days; maximum duration of treatment 14 days (including treatment by intravenous or intramuscular injection) ▶BY INTRAVENOUS INJECTION, OR BY INTRAMUSCULAR INJECTION ▶Adult: 20 mg once daily as initial treatment for 1–2 days if oral administration not possible

Source page 1236

Contra Indications

Active gastro-intestinal bleeding. active gastro-intestinal ulceration. history of gastro- intestinal bleeding related to previous NSAID therapy. history of gastro-intestinal perforation related to previous NSAID therapy. history of recurrent gastro-intestinal haemorrhage (two or more distinct episodes). history of recurrent gastro-intestinal ulceration (two or more distinct episodes). severe heart failure

Source page 1236

Cautions

Allergic disorders. cardiac impairment (NSAIDs may impair renal function). cerebrovascular disease. coagulation defects. connective-tissue disorders. dehydration (risk of renal impairment). elderly (risk of serious side-effects and fatalities). heart failure. history of gastro-intestinal disorders (e.g. ulcerative colitis, Crohn’s disease). ischaemic heart disease. peripheral arterial disease. risk factors for cardiovascular events. uncontrolled hypertension

Source page 1236

Allergy And Cross Sensitivity

Contra-indicated in patients with a history of hypersensitivity to aspirin or any other NSAID—which includes those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID.

Source page 1237

Safety

Extracted information for Tenoxicam only.

Interactions

→Appendix 1: NSAIDs

Source page 1236

Side Effects

GENERAL SIDE-EFFECTS ▶Common or very common Constipation. Crohn’s disease aggravated. diarrhoea. gastrointestinal discomfort. gastrointestinal disorders. haemorrhage. headache. nausea. vomiting ▶Uncommon Fatigue. oedema. skin reactions ▶Rare or very rare Asthma. bronchospasm. depression. dyspnoea. hyperglycaemia. nervousness. palpitations. pancreatitis. severe cutaneous adverse reactions (SCARs). sleep disorders. vertigo. weight changes ▶Frequency not known Agranulocytosis. alopecia. anaemia. angioedema. aplastic anaemia. confusion. eosinophilia. fertility decreased female. haemolytic anaemia. hallucination. heart failure. hepatic disorders. hypersensitivity. hypertension. leucopenia. malaise. nail disorder. nephritis tubulointerstitial. nephropathy. paraesthesia. photosensitivity reaction. platelet aggregation inhibition. purpura non-thrombocytopenic. renal failure (more common in patients with pre-existing renal impairment). thrombocytopenia. tinnitus. vasculitis . vision disorders SPECIFIC SIDE-EFFECTS ▶Common or very common ▶With oral use Dizziness. dry mouth. oral disorders ▶Rare or very rare ▶With oral use Embolism and thrombosis. metabolic disorder ▶Frequency not known ▶With oral use Drowsiness. eye irritation. eye swelling ▶With parenteral use Appetite decreased. increased risk of arterial thromboembolism. increased risk of ischaemic stroke. increased risk of myocardial infarction. meningitis aseptic (patients with connective-tissue disorders such as systemic lupus erythematosus may be especially susceptible). neutropenia. oral ulceration SIDE-EFFECTS, FURTHER INFORMATION For information about cardiovascular and gastrointestinal side-effects, and a possible exacerbation of symptoms in asthma, see Non- steroidal anti-inﬂammatory drugs. p. 1193

Source pages 1236, 1237

Conception And Contraception

Caution—long-term use of some NSAIDs is associated with reduced female fertility, which is reversible on stopping treatment.

Source page 1237

Pregnancy

Avoid unless the potential beneﬁt outweighs the risk. Avoid during the third trimester (risk of closure of fetal ductus arteriosus in utero and possibly persistent pulmonary hypertension of the newborn); onset of labour may be delayed and duration may be increased.

Source page 1237

Breast Feeding

Use with caution during breast-feeding. Present in milk in animal studies.

Source page 1237

Hepatic Impairment

Manufacturer advises caution in mild to moderate impairment; avoid in severe impairment.

Source page 1237

Renal Impairment

Avoid if possible or use with caution. Avoid in severe impairment. Dose adjustments The lowest effective dose should be used for the shortest possible duration. Monitoring In renal impairment monitor renal function; sodium and water retention may occur and renal function may deteriorate, possibly leading to renal failure.

Source page 1237

Dose and formulations

Extracted information for Tenoxicam only.

Medicinal Forms

There can be variation in the licensing of different medicines containing the same drug. Powder and solvent for solution for injection ▶Tenoxicam (Non-proprietary) Tenoxicam 20 mg Tenoxicam 20mg powder and solvent for solution for injection vials | 1 vial P £3.98 Tablet CAUTIONARY AND ADVISORY LABELS 21 ▶Mobiflex (Mylan) Tenoxicam 20 mg Mobiflex 20mg tablets | 30 tablet P £13.42 DT = £13.42

Source page 1237

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily as initial treatment for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily for 7 days; maximum duration

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily as initial treatment for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.

Individual generic drug information

tenoxicam

Reference monograph

Part of registered formulation

TENOXICAM

Reference record: Tenoxicam
Source: BNF 80 (2020–2021)
Printed source pages: 1236, 1237
Age groups indexed: 1

Individual active ingredientSource records are displayed separately

Some source sections could not be separated reliably in the extraction. Review the printed source pages when a field is missing or incomplete.

Overview

Extracted information for Tenoxicam only.

Indications And Dose

Source page 1236

Contra Indications

Source page 1236

Cautions

Source page 1236

Allergy And Cross Sensitivity

Source page 1237

Safety

Extracted information for Tenoxicam only.

Interactions

→Appendix 1: NSAIDs

Source page 1236

Side Effects

Source pages 1236, 1237

Conception And Contraception

Caution—long-term use of some NSAIDs is associated with reduced female fertility, which is reversible on stopping treatment.

Source page 1237

Pregnancy

Source page 1237

Breast Feeding

Use with caution during breast-feeding. Present in milk in animal studies.

Source page 1237

Hepatic Impairment

Manufacturer advises caution in mild to moderate impairment; avoid in severe impairment.

Source page 1237

Renal Impairment

Source page 1237

Dose and formulations

Extracted information for Tenoxicam only.

Medicinal Forms

Source page 1237

Dose text by age group

Filter the extracted dose blocks for this individual drug.

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily as initial treatment for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily for 7 days; maximum duration

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Adults

First line only; read the complete Indications and dose section above.

20 mg once daily as initial treatment for

This is a first-line fragment. Read the full Indications and Dose section above.

Candidate age grouping · source page 1236

Age labels are extracted from the printed dose headings and require clinical review. Confirm current local guidance, dose, route, formulation, contraindications and interactions before prescribing.