Individual generic drug information
Extracted information for Dexketoprofen only.
Short-term treatment of mild to moderate pain including dysmenorrhoea ▶BY MOUTH ▶Adult: 12.5 mg every 4–6 hours, alternatively 25 mg every 8 hours; maximum 75 mg per day ▶Elderly: 12.5 mg every 4–6 hours, alternatively 25 mg every 8 hours, initial max. 50 mg; maximum 75 mg daily
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Active bleeding or bleeding disorders. active or recurrent gastro-intestinal haemorrhage. active or recurrent gastro-intestinal ulcer. chronic dyspepsia. Crohn’s disease. history of NSAID- associated gastro-intestinal bleeding or perforation. known photoallergic or phototoxic reactions during treatment with ketoprofen or fibrates. severe dehydration . severe heart failure. ulcerative colitis. varicella infection
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Allergic disorders. asthma. cerebrovascular disease. coagulation defects. congenital disorder of porphyrin metabolism. congestive heart failure. dehydration. elderly (risk of serious side-effects and fatalities). following major surgery. haematopoietic disorders. history of cardiac disease (NSAIDs may cause fluid retention and oedema). history of gastro-intestinal disease. history of gastro-intestinal toxicity. ischaemic heart disease. mixed connective-tissue disorders. peripheral arterial disease. risk factors for cardiovascular events. systemic lupus erythematosus. uncontrolled hypertension
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Contra-indicated in patients with a history of hypersensitivity to aspirin or any other NSAID—which includes those in whom attacks of asthma, angioedema, urticaria or rhinitis have been precipitated by aspirin or any other NSAID. Musculoskeletal system
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Extracted information for Dexketoprofen only.
→Appendix 1: NSAIDs
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▶Common or very common Diarrhoea. gastrointestinal discomfort. nausea. vomiting ▶Uncommon Anxiety. asthenia. chills. constipation. dizziness. drowsiness. dry mouth. flushing. gastrointestinal disorders. headache. insomnia. malaise. pain. palpitations. skin reactions. vertigo ▶Rare or very rare Angioedema. appetite decreased. dyspnoea. haemorrhage. hepatic disorders. hyperhidrosis . hypersensitivity. hypertension. hypotension. menstrual disorder. nephritis. nephrotic syndrome. neutropenia. oedema. pancreatitis. paraesthesia. photosensitivity reaction. polyuria. prostatic disorder. respiratory disorders. severe cutaneous adverse reactions (SCARs). syncope. tachycardia. thrombocytopenia. tinnitus. vision blurred ▶Frequency not known Acute kidney injury (more common in patients with pre-existing renal impairment). agranulocytosis. anaemia. aplastic anaemia. haemolytic anaemia. inflammatory bowel disease. meningitis aseptic . oral ulceration. platelet aggregation inhibition. renal papillary necrosis SIDE-EFFECTS, FURTHER INFORMATION For information about cardiovascular and gastrointestinal side-effects, and a possible exacerbation of symptoms in asthma, see Non- steroidal anti-inflammatory drugs. p. 1193
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Caution—long-term use of some NSAIDs is associated with reduced female fertility, which is reversible on stopping treatment.
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Avoid unless the potential benefit outweighs the risk. Avoid during the third trimester (risk of closure of fetal ductus arteriosus in utero and possibly persistent pulmonary hypertension of the newborn); onset of labour may be delayed and duration may be increased.
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Use with caution during breast-feeding. Manufacturer advises avoid—no information available.
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Manufacturer advises caution in mild to moderate impairment; avoid in severe impairment. Dose adjustments Manufacturer advises initial dose reduction to max. 50 mg daily in mild to moderate impairment.
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Avoid if possible or use with caution. Avoid in moderate to severe impairment. Dose adjustments Reduce initial dose to 50 mg daily. The lowest effective dose should be used for the shortest possible duration. Monitoring In renal impairment monitor renal function; sodium and water retention may occur and renal function may deteriorate, possibly leading to renal failure.
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Extracted information for Dexketoprofen only.
There can be variation in the licensing of different medicines containing the same drug. Tablet CAUTIONARY AND ADVISORY LABELS 22 ▶Keral (A. Menarini Farmaceutica Internazionale SRL) Dexketoprofen (as Dexketoprofen trometamol) 25 mg Keral 25mg tablets | 20 tablet P £3.67 | 50 tablet P £9.18 DT = £9.18 Combinations available: Tramadol with dexketoprofen, p. 494
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Filter the extracted dose blocks for this individual drug.
First line only; read the complete Indications and dose section above.
12.5 mg every 4–6 hours, alternatively 25 mg
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 1219
First line only; read the complete Indications and dose section above.
12.5 mg every 4–6 hours, alternatively 25 mg
This is a first-line fragment. Read the full Indications and Dose section above.
Candidate age grouping · source page 1219
